Comprehensive Guide to 2-Bromopyridin-3-ylboronic Acid
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industrial Uses
- 3. Usage Guidelines & Best Practices
- 4. Comparative Analysis with Alternative Boronic Acids
- 5. Real-World Case Studies
- 6. Technical Inquiry & Ordering Information
1. Product Overview & Specifications
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| CAS Number | 1072944-20-8 | 1072944-20-8 | 1072944-20-8 |
| Purity | ≥97% (HPLC) | ≥95% | ≥96% |
| Molecular Formula | C5H4BBrNO2 | Same | Same |
| Storage Temperature | 2-8°C (desiccated) | Room temperature | 2-8°C |
2. Key Applications & Industrial Uses
This boronic acid derivative is essential for:
- Suzuki-Miyaura cross-coupling reactions
- Pharmaceutical intermediates for kinase inhibitors
- Agrochemical synthesis
- Material science applications
3. Usage Guidelines & Best Practices
Optimal handling requires:
- Inert atmosphere handling (N2 or Ar)
- Anhydrous reaction conditions
- Catalyst optimization (Pd(PPh3)4 vs. Pd(dppf)Cl2)
4. Comparative Analysis
| Feature | 2-Bromopyridin-3-ylboronic Acid | 2-Chloropyridin-4-ylboronic Acid |
|---|---|---|
| Reactivity | High (Br activates position) | Moderate |
| Pharma Applications | JAK inhibitors | EGFR inhibitors |
5. Real-World Case Studies
Case 1: Leading Pharma Company (2023)
Developed Bruton’s tyrosine kinase (BTK) inhibitor using this compound as key intermediate, achieving 92% coupling yield.
Case 2: University Research Team (2024)
Created novel OLED materials demonstrating 15% improvement in electron mobility.
6. Technical Inquiry & Ordering
Contact our chemists for:
- Custom synthesis options
- Bulk pricing (10kg+ quantities)
- Regulatory documentation support
Email: info@vivalr.com
Tel: (86) 15866781826
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