Product Name:6-(Chloromethyl)uracil
CAS:18592-13-7
MFC5H5ClN2O2
MW:160.56
EINECS:242-431-9
MOL File:18592-13-7.mol
Parameter | 6-(Chloromethyl)uracil | 5-(Chloromethyl)uracil | Unsubstituted Uracil |
---|---|---|---|
CAS Number | 53902-25-7 | N/A | 66-22-8 |
Molecular Formula | C5H5ClN2O2 | C5H5ClN2O2 | C4H4N2O2 |
Purity | >98% (HPLC) | 95-97% | 99% |
Reactivity | High (Chloromethyl group) | Moderate | Low |
Enables precise molecular modifications in antiviral drug development (e.g., nucleoside analogs)
Facilitates covalent bonding in smart material synthesis through its reactive chloromethyl group
Store at 2-8°C under inert gas with desiccant
Use polar aprotic solvents (DMF/DMSO) at 40-60°C for nucleophilic substitutions
Modified uracil derivatives for targeted chemotherapy agents
Fluorescent labeling applications in molecular diagnostics
Challenge: Needed stable intermediate for HCV protease inhibitor
Solution: Customized 6-(Chloromethyl)uracil synthesis
Result: 22% yield improvement vs traditional routes
Challenge: Required modified nucleobases for mRNA vaccine research
Solution: Batch-specific purity optimization
Result: Achieved 99.2% purity for critical conjugation steps
Contact our technical team for:
- Bulk pricing
- Custom synthesis
- Regulatory support
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