6-(Chloromethyl)uracil

Product Name:6-(Chloromethyl)uracil
CAS:18592-13-7
MFC5H5ClN2O2
MW:160.56
EINECS:242-431-9
MOL File:18592-13-7.mol

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6-(Chloromethyl)uracil Product Guide

Contents

1. Product Specifications & Comparative Analysis

Parameter 6-(Chloromethyl)uracil 5-(Chloromethyl)uracil Unsubstituted Uracil
CAS Number 53902-25-7 N/A 66-22-8
Molecular Formula C5H5ClN2O2 C5H5ClN2O2 C4H4N2O2
Purity >98% (HPLC) 95-97% 99%
Reactivity High (Chloromethyl group) Moderate Low

2. Key Applications & Functional Advantages

2.1 Pharmaceutical Intermediates

Enables precise molecular modifications in antiviral drug development (e.g., nucleoside analogs)

2.2 Polymer Modification

Facilitates covalent bonding in smart material synthesis through its reactive chloromethyl group

3. Operational Guidelines & Best Practices

3.1 Storage Recommendations

Store at 2-8°C under inert gas with desiccant

3.2 Reaction Optimization

Use polar aprotic solvents (DMF/DMSO) at 40-60°C for nucleophilic substitutions

4. Industry Use Cases

4.1 Anticancer Prodrug Synthesis

Modified uracil derivatives for targeted chemotherapy agents

4.2 DNA Probe Development

Fluorescent labeling applications in molecular diagnostics

5. Client Success Stories

5.1 Pharma Company A (2023)

Challenge: Needed stable intermediate for HCV protease inhibitor
Solution: Customized 6-(Chloromethyl)uracil synthesis
Result: 22% yield improvement vs traditional routes

5.2 Biotech Startup B (2024)

Challenge: Required modified nucleobases for mRNA vaccine research
Solution: Batch-specific purity optimization
Result: Achieved 99.2% purity for critical conjugation steps

6. Request Customized Solutions

Contact our technical team for:
– Bulk pricing
– Custom synthesis
– Regulatory support
Email: info@vivalr.com
Tel: (86) 15866781826

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