Methyl 4-aminopyridine-3-carboxylate

Product Name:Methyl 4-aminopyridine-3-carboxylate
CAS:16135-36-7
MFC7H8N2O2
MW:152.15
EINECS:
MOL File:16135-36-7.mol

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Methyl 4-Aminopyridine-3-Carboxylate Product Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Methyl 4-Aminopyridine-3-Carboxylate 4-Aminopyridine Ethyl Ester Analog
CAS Number 118943-21-6 504-24-5 N/A
Molecular Formula C7H8N2O2 C5H6N2 C8H10N2O2
Purity >98% (HPLC) >95% >97%
Solubility DMSO, Ethanol Water, DMSO Ethyl Acetate

2. Applications & Industrial Uses

Pharmaceutical Intermediates

Used in synthesizing kinase inhibitors and neurological drug candidates with enhanced blood-brain barrier permeability.

Organic Catalysis

Facilitates Knoevenagel condensations in asymmetric synthesis under mild conditions (60°C, 12h).

Electronics Materials

Precursor for conductive polymers in OLED displays, achieving 15% higher luminescence efficiency.

3. Operational Guidelines

Storage

-20°C under argon, shelf life: 24 months. Reconstitute in anhydrous DMSO for bioassays.

Reaction Protocol

Typical coupling reaction: 1.2 eq. reagent, DCM solvent, 0°C to RT, 85% average yield.

4. Case Studies

Pharma API Scale-Up

Client: EU-based CDMO
Challenge: Improve intermediate stability
Solution: Methyl ester formulation reduced degradation by 40% at 25°C
Outcome: Achieved 500kg batch compliance with ICH Q3C

5. Client Success Stories

Case 1: Agrochem Innovator (USA)

Application: Herbicide safener synthesis
Volume: 120kg/year
Result: 22% field efficacy improvement vs. ethyl analogs

Case 2: Battery Tech Startup (South Korea)

Application: Solid-state electrolyte additive
Result: 18% ionic conductivity increase at -30°C

6. Request Customized Solutions

Contact our technical team for:

  • Bulk pricing (50kg+ orders)
  • GMP-grade synthesis
  • Custom derivatization services

Email: info@vivalr.com
Phone: (86) 15866781826

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