6-Chloro-2-methyl-3-nitropyridine: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Basic Information
- Chemical Name: 6-Chloro-2-methyl-3-nitropyridine
- CAS Number: 22280-60-0
- Molecular Formula: C6H5ClN2O2
- Molecular Weight: 172.57 g/mol
- Appearance: Pale yellow crystalline solid
- Purity: ≥98% (GC)
Physical-Chemical Properties
| Parameter | Value |
|---|---|
| Melting Point | 53–57°C |
| Boiling Point | 255.9°C at 760 mmHg |
| Density | 1.406 g/cm³ |
| Flash Point | 108.5°C |
| Refractive Index | 1.575 |
Supplier Comparison
| Brand | Purity | Packaging | Price (USD) |
|---|---|---|---|
| Acmec | 98% | 25g, 100g | $35.90 (25g), $127.50 (100g) |
| Tanmo Quality | 98% | 1g | $30.00 |
2. Key Applications
6-Chloro-2-methyl-3-nitropyridine serves as a critical intermediate in:
- Pharmaceutical Synthesis: Production of antiviral agents and kinase inhibitors.
- Agrochemicals: Development of herbicides and pesticides.
- Material Science: Precursor for functionalized polymers and coordination complexes.
3. Usage Guidelines
Recommended Workflow
- Storage: Keep in a cool, dry place (≤25°C) away from light and moisture.
- Handling: Use under fume hood with nitrile gloves and safety goggles.
- Reaction Conditions: Optimize at 60–80°C in inert solvents (e.g., DMF, THF).
4. Safety & Handling
Hazard Classification (GHS)
- H315: Causes skin irritation
- H319: Causes serious eye irritation
- H335: May cause respiratory irritation
Preventive Measures
- Use PPE: Lab coat, gloves, and face shield.
- Avoid inhalation; ensure proper ventilation.
5. Client Case Studies
Case Study 1: Antiviral Drug Development
Client: A European pharmaceutical company utilized the compound to synthesize a novel RNA polymerase inhibitor, achieving 92% yield in key coupling reactions.
Case Study 2: Herbicide Formulation
Client: An agrochemical manufacturer integrated the product into a next-generation herbicide, enhancing weed-control efficacy by 40%.
6. Contact for Inquiries
For pricing, bulk orders, or technical support:
- Email: info@vivalr.com
- Phone: (86) 15866781826


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