4-AMINO-2-CHLOROPYRIDINE

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4-Amino-2-chloropyridine: Comprehensive User Guide

1. Product Overview & Specifications

4-Amino-2-chloropyridine (CAS 14432-12-3) is a halogenated pyridine derivative widely used in pharmaceutical and agrochemical synthesis. Key parameters:

Parameter Specification Competitor A Competitor B
Purity ≥99% ≥98% ≥97.5%
Melting Point 89-92°C 87-90°C 85-88°C
Solubility Soluble in ethanol, DMF Limited in DMF Poor in ethanol

2. Key Applications

Pharmaceutical Intermediate

Critical for synthesizing antiviral agents and kinase inhibitors due to its dual functional groups enabling selective modifications.

Agrochemical Production

Used in neonicotinoid insecticide precursors with 30% higher reaction yield compared to traditional intermediates.

3. Usage Guidelines

Reaction Conditions

  • Optimal temperature range: 40-60°C
  • pH stability: 6.0-8.0

Safety Protocols

Parameter Requirement
Storage 2-8°C in amber glass
PPE Nitrile gloves, vapor respirator

4. Industry Use Cases

Case 1: Anticancer Drug Synthesis

Used as key building block in PD-1/PD-L1 inhibitors, achieving 92% coupling efficiency in Suzuki-Miyaura reactions.

5. Client Success Stories

Shanghai PharmTech Co., Ltd.

Achieved 40% cost reduction in c-Met inhibitor production through optimized amination processes using our 4-amino-2-chloropyridine.

Nanjing AgroSolutions

Developed next-generation systemic insecticides with 15% improved field efficacy using our high-purity compound.

Request Customized Solutions

Email: info@vivalr.com
Tel: (86) 15866781826




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