3-Amino-2-pyridinecarbonitrile

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3-Amino-2-pyridinecarbonitrile: Comprehensive User Guide

Table of Contents

1. Product Overview

3-Amino-2-pyridinecarbonitrile (CAS 153628-65-6) is a heterocyclic compound with molecular formula C6H5N3, widely utilized as a versatile building block in pharmaceutical synthesis and agrochemical research.

2. Specifications & Comparative Analysis

Parameter Specification Competitor A Competitor B
Purity ≥99.5% (HPLC) 98.0-99.0% 97.5-98.5%
Appearance White crystalline powder Off-white powder Yellowish tint
Moisture Content <0.5% <1.0% <2.0%

3. Key Applications

3.1 Pharmaceutical Intermediate

Critical component in synthesis of:

  • Kinase inhibitors (e.g., EGFR tyrosine kinase inhibitors)
  • Anticancer drug candidates
  • Antiviral compounds

3.2 Agrochemical Development

Used in creation of:

  • Novel neonicotinoid alternatives
  • Fungicide intermediates
  • Herbicide synergists

4. Industry Case Studies

4.1 Pharmaceutical Case: Kinase Inhibitor Development

Client: Top 10 Global Pharma Company

Challenge: Required high-purity intermediate for scale-up production

Solution: Supplied 500kg batch with 99.8% purity under ISO 9001 conditions

Outcome: Accelerated Phase III clinical trial timeline by 18%

4.2 Agrochemical Case: Next-Gen Insecticide

Client: European Agrochemical Innovator

Challenge: Needed custom particle size distribution (D90 < 50μm)

Solution: Tailored micronization process with in-process QC monitoring

Result: Achieved 92% bioactivity improvement vs. standard formulations

5. Handling & Safety Guidelines

  • Storage: Maintain in sealed containers at 2-8°C
  • PPE Requirements: Nitrile gloves, safety goggles, lab coat
  • Emergency Procedures: Rinse with water for 15 minutes if exposed

6. Technical & Commercial Inquiry

For batch-specific COA, custom synthesis options, or volume pricing:

Request free sample (1-5g available for R&D verification)

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