4-Chloro-3-pyridinesulfonamide

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4-Chloro-3-pyridinesulfonamide: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

4-Chloro-3-pyridinesulfonamide (CAS 144330-52-3) is a high-purity sulfonamide derivative extensively used in pharmaceutical and agrochemical synthesis.

Parameter Specification
Molecular Formula C5H5ClN2O2S
Molecular Weight 192.63 g/mol
Appearance White to off-white crystalline powder
Purity (HPLC) ≥99%
Melting Point 218-222°C
Storage 2-8°C in dry environment

2. Key Applications & Industry Uses

Pharmaceutical Intermediate

Critical component in kinase inhibitor development for cancer therapeutics

Agrochemical Synthesis

Building block for novel sulfonylurea-class herbicides

Chemical Research

Precursor in organocatalyst development and coordination chemistry

3. Operational Guidelines & Safety

Parameter Requirement
Handling Use NIOSH-approved respirator & chemical gloves
Solubility DMSO: 50 mg/mL; Water: <1 mg/mL
Incompatibilities Strong oxidizers, concentrated acids

4. Comparative Analysis

Compound Reactivity Cost Efficiency Thermal Stability
4-Chloro-3-pyridinesulfonamide High ★★★★☆ 220°C
3-Chloro isomer Medium ★★★☆☆ 205°C
4-Fluoro analog Low ★★☆☆☆ 195°C

5. Real-World Use Cases

Case 1: Anticancer Drug Development

Used as key intermediate in third-generation EGFR inhibitors showing 92% yield improvement

Case 2: Herbicide Formulation

Enabled 40% cost reduction in sulfonylurea herbicide production for major agrochemical company

6. Customer Success Stories

PharmaTech Innovations

Reduced lead compound synthesis time from 14 to 6 days using our GMP-grade material

AgroSolutions Ltd.

Achieved 99.7% purity in final herbicide product using our optimized sulfonamide derivatives

7. Request Customized Quotes

Contact our technical team for batch-specific COA and volume pricing:

Email: info@vivalr.com
Phone: (86) 15866781826

★ Bulk Order Discount: 15% off orders >50kg ★

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