2-PYRIMIDINECARBOXYLIC ACID, METHYL ESTER

2-Pyrimidinecarboxylic Acid, Methyl Ester: Comprehensive Guide

1. Product Overview & Specifications

CAS No.: 31462-59-2
Molecular Formula: C7H8N2O2
Molecular Weight: 152.15 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
Storage: 2-8°C in airtight container

2. Key Applications

• Pharmaceutical Intermediates: Synthesis of antiviral agents and kinase inhibitors
• Agrochemicals: Building block for herbicidal compounds
• Organic Synthesis: Carboxyl group protection in nucleophilic substitutions
• Research Chemicals: Ligand preparation in coordination chemistry

3. Usage Guidelines

Handling Precautions:
– Use PPE including nitrile gloves and safety goggles
– Avoid dust generation in poorly ventilated areas
Reaction Optimization:
– Typical dosage: 1.2-1.5 molar equivalents
– Compatible with THF, DCM, and DMF solvents
Storage Recommendations:
– Nitrogen atmosphere for long-term storage
– Desiccate to prevent hydrolysis

4. Industrial Case Studies

Case 1: Antiviral Drug Synthesis
– Client: European Pharma Company (Confidential)
– Application: Key intermediate in RNA polymerase inhibitor production
– Result: 22% yield improvement vs. previous synthesis route

Case 2: Herbicide Development
– Client: US Agrochemical Manufacturer
– Application: Pyrimidine core modification for selective weed control
– Outcome: Patent-pending formulation with 98.7% target purity

5. Client Success Stories

Client A: Japanese Research Institute
– Usage: Coordination complexes for catalytic studies
– Feedback: “Consistent HPLC purity enabled reproducible results in our asymmetric hydrogenation trials”

Client B: Indian Generic Drug Manufacturer
– Application: Scale-up of diabetes medication intermediates
– Volume: 850kg annual procurement
– Testimonial: “Reliable supply chain and technical support ensured smooth API production”

6. Request Custom Quotes

Explore batch-specific certificates of analysis and bulk pricing:
Email: info@vivalr.com
Phone: (86) 15866781826
Available in 100g, 1kg, and 25kg commercial quantities. Custom synthesis options for modified pyrimidine derivatives.