4-Pyridineacetic acid hydrochloride

Comprehensive Guide to 4-Pyridineacetic Acid Hydrochloride (CAS: 6622-91-9)

Table of Contents

1. Product Specifications & Comparative Analysis
2. Applications & Industrial Uses
3. Operational Guidelines & Best Practices
4. Case Studies
5. Procurement & Safety Considerations
6. Inquiry & Contact

1. Product Specifications & Comparative Analysis

2. Applications & Industrial Uses

2.1 Pharmaceutical Intermediates

Widely used in synthesizing active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and neurological agents. Its pyridine moiety enables selective binding to biological targets.

2.2 Agrochemical Development

Functions as a precursor for herbicides and fungicides due to its stability under harsh reaction conditions. Example: Synthesis of pyridine-based plant growth regulators.

2.3 Material Science

Employed in metal-organic frameworks (MOFs) and coordination polymers, leveraging its carboxylate group for molecular assembly.

3. Operational Guidelines & Best Practices

3.1 Handling Protocols

• Storage: Keep in airtight containers at 2-8°C with desiccants
• Ventilation: Use fume hoods during weighing/dissolution
• Incompatibilities: Avoid strong oxidizers and bases

3.2 Solubility Profile

4. Case Studies

4.1 PharmaTech Inc. (Anticancer Drug Development)

Challenge: Low yield in EGFR inhibitor synthesis
Solution: Implemented 4-Pyridineacetic Acid HCl as coupling agent
Result: 37% yield improvement with 99.2% purity

4.2 AgroSolutions Ltd. (Herbicide Formulation)

Challenge: Photodegradation of active components
Solution: Added 0.5% w/w as stabilizer
Result: Shelf life extended from 6 to 18 months

5. Procurement & Safety Considerations

5.1 Supplier Evaluation Criteria

• Certification: ISO 9001, REACH compliance
• Purity: ≥98% (HPLC verified)
• Batch Consistency: ≤2% variability in impurity profile

5.2 Emergency Procedures

6. Inquiry & Contact

For technical specifications, COA, or bulk pricing:

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