2-Mercaptonicotinic Acid: Comprehensive Product Guide

Table of Contents

Product Overview

2-Mercaptonicotinic acid (CAS 38521-46-9) is a sulfur-containing derivative of nicotinic acid, widely used in pharmaceutical synthesis, biochemical research, and material science. Key properties include:

  • Molecular Formula: C6H5NO2S
  • Appearance: White to off-white crystalline powder
  • Purity: ≥98% (HPLC)
  • Solubility: Soluble in DMSO, methanol, and alkaline solutions

Specifications & Comparative Analysis

Parameter 2-Mercaptonicotinic Acid Similar Thiol Compounds
Thermal Stability Stable up to 200°C Decomposes at 150-180°C
Reactivity High nucleophilic activity Moderate reactivity
Pharmaceutical Compatibility Ideal for API synthesis Limited applications

Detailed Applications

Pharmaceutical Industry

Critical intermediate for:

  • Antibacterial drug synthesis
  • HIV protease inhibitors
  • Metal-chelating therapeutic agents

Material Science

Used in:

  • Surface modification of nanoparticles
  • Coordination polymer development
  • Catalyst preparation

Usage Scenarios

Scenario 1: Pharmaceutical R&D

Used as a key building block in multi-step synthesis of novel antimicrobial agents, demonstrating 92% reaction efficiency in optimized conditions.

Scenario 2: Industrial Catalysis

Employed in cross-coupling reactions for polymer production, achieving 15% higher yield compared to traditional catalysts.

Client Success Stories

Case 1: PharmaHealth Inc.

Challenge: Needed stable thiol precursor for antiviral drug development
Solution: Customized 99% purity grade with enhanced solubility
Outcome: Reduced synthesis steps from 7 to 4, saving 40% in production costs

Case 2: NanoTech Materials

Challenge: Required precise surface functionalization of quantum dots
Solution: Ultra-pure batch (99.8%) with particle size optimization
Outcome: Achieved 98% monolayer coverage in nanoparticle assembly

Request a Quote

Optimize your research or production with our premium-grade 2-Mercaptonicotinic Acid. Contact our technical team:

Email: info@vivalr.com
Phone: (86) 15866781826

Request custom synthesis, bulk pricing, or SDS documentation.

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