1. Product Overview & Specifications

Key Parameters

Competitive Advantages

• Superior reactivity in nucleophilic substitution reactions
• Enhanced solubility profile for diverse reaction conditions
• Higher thermal stability vs. non-fluorinated analogs

2. Applications & Use Cases

Pharmaceutical Intermediate

Critical for synthesizing fluorinated API precursors in:

• Anticancer agents (e.g., kinase inhibitors)
• Neurological therapeutics
• Antiviral compounds

Agrochemical Synthesis

Enables development of advanced:

• Herbicides with improved crop selectivity
• Insecticides featuring fluorine-enhanced bioactivity

3. Step-by-Step Usage Guidelines

Standard Reaction Protocol

1. Prepare 0.1M solution in anhydrous DMF
2. Maintain reaction temperature at -10°C to 25°C
3. Use inert atmosphere (N₂/Ar) for oxygen-sensitive reactions
4. Monitor conversion via HPLC at 254nm

Safety Handling

• PPE Requirement: Nitrile gloves, chemical goggles
• Storage: Keep in amber glass at 2-8°C
• Shelf Life: 24 months unopened

4. Industry Case Studies

Case 1: Antiviral Drug Development

Challenge: Improve yield in fluorinated nucleoside synthesis
Solution: 3-Fluoropyridine N-Oxide-mediated coupling reaction
Result: 82% yield vs. 58% with traditional methods

Case 2: OLED Material Production

Challenge: Achieve precise fluorination in electron transport layers
Solution: Directed ortho-metalation using N-oxide derivative
Result: 15% improvement in device luminance efficiency

5. Client Success Stories

PharmaTech Solutions (Munich)

Project: Development of third-generation EGFR inhibitors
Application: Key fluorination agent in lead optimization
Outcome: Reduced IC50 from 48nM to 9nM in 6-month cycle

AgroNova Ltd. (Shanghai)

Project: Next-gen fungicide formulation
Application: Building block for systemic activity enhancement
Outcome: Field efficacy increased by 40% at half dosage

6. Contact for Custom Solutions

Optimize your fluorination chemistry with our technical support:

• Email: info@vivalr.com
• Phone: (86) 15866781826

Request batch-specific COA or discuss bulk order discounts.