(2-Aminopyridin-3-yl)methanol

Comprehensive Guide to (2-Aminopyridin-3-yl)methanol

Table of Contents

• Product Overview & Specifications
• Applications & Industrial Uses
• Usage Guidelines
• Case Studies
• Client Testimonials
• Request a Quote

Product Overview & Specifications

Chemical Name: (2-Aminopyridin-3-yl)methanol

CAS Number: 1000408-47-0

Molecular Formula: C6H8N2O

Molecular Weight: 124.14 g/mol

Key Parameters Comparison

Applications & Industrial Uses

Widely used as:

• Pharmaceutical Intermediate: Key precursor in kinase inhibitor synthesis (e.g., EGFR inhibitors).
• Agrochemicals: Building block for fungicide development.
• Material Science: Ligand in coordination polymers for catalytic applications.

Usage Guidelines

1. Handle under inert gas (N2/Ar) for moisture-sensitive reactions.
2. Recommended storage: 2-8°C in sealed containers with desiccant.
3. Use PPE (gloves, goggles) during handling per SDS guidelines.

Case Studies

Case 1: Anticancer Drug Intermediate

Challenge: Low yield (42%) in Osimertinib analog synthesis.

Solution: Optimized coupling reaction using (2-Aminopyridin-3-yl)methanol at -15°C.

Result: Yield increased to 78% with 99.2% HPLC purity.

Case 2: Fungicide Development

Challenge: Poor bioavailability in crop protection agents.

Solution: Structural modification via methanol group functionalization.

Result: 5x improvement in systemic mobility through plant tissues.

Client Testimonials

PharmaSynth Inc. (USA)

“Consistent ≥98% purity reduced our purification costs by 30% in kinase inhibitor projects.”

AgroChem Solutions GmbH (Germany)

“Technical support helped develop a novel fungicide formulation within 6 months.”

UniMaterials Co., Ltd. (China)

“Reliable bulk supply enabled scalable production of MOF catalysts.”

Request a Quote

Contact our team for:

• Custom synthesis (mg to kg scale)
• Bulk pricing (≥100kg orders)
• Regulatory documentation support

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