1. Product Overview & Specifications

2-Amino-4-methoxypyridine (CAS 17252-51-6) is a versatile heterocyclic compound widely used in pharmaceutical synthesis and organic chemistry. Key specifications include:

2. Key Applications

Pharmaceutical Intermediates

Critical for synthesizing kinase inhibitors and antiviral agents, with enhanced solubility compared to pyridine derivatives.

Organic Catalysis

Facilitates Suzuki-Miyaura couplings and Buchwald-Hartwig aminations due to electron-rich amino-methoxy structure.

Material Science

Used in coordination polymers and metal-organic frameworks (MOFs) for gas storage applications.

3. Usage Protocols

Example 1: Anticancer Drug Synthesis

1. Charge reactor with 2-Amino-4-methoxypyridine (1.2 eq)
2. Add palladium catalyst (0.05 mol%) under N₂
3. Heat to 80°C for 6 hours
4. Purify via column chromatography (hexane/EA 3:1)

Example 2: MOF Preparation

1. Dissolve 5g compound in DMF (50ml)
2. Add Zn(NO₃)₂·6H₂O (2 eq)
3. Hydrothermal treatment at 120°C for 48h
4. Activate at 150°C under vacuum

4. Customer Success Stories

Case 1: Top 10 Pharma Company

Challenge: Low yield (32%) in kinase inhibitor scale-up
Solution: Optimized using our ≥99% grade
Result: Yield increased to 68%, reduced purification steps

Case 2: University Research Team

Challenge: Unstable MOF structure
Solution: Implemented our batch-controlled material
Result: Achieved 94% porosity with 12-month stability

5. Request Customized Solutions

Contact our technical team for batch-specific COAs or formulation support:

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