Parameter | 3-Bromo-2,5-Dichloropyridine | Similar Compounds |
---|---|---|
CAS Number | NA | Varies by derivative |
Molecular Formula | C5H2BrCl2N | Dependent on substitution |
Molecular Weight | 247.34 g/mol | Generally 200-300 g/mol |
Appearance | White to off-white crystalline powder | Similar physical form |
Purity | ≥98% (HPLC) | Typically 95-99% |
Storage Conditions | 2-8°C in airtight container | Consistent with halogenated pyridines |
Pharmaceutical Intermediates: Key building block for kinase inhibitors and antiviral agents.
Agrochemical Synthesis: Precursor for advanced crop protection chemicals.
Material Science: Used in OLED materials and conductive polymers.
Handling Protocols: Use nitrogen atmosphere for moisture-sensitive reactions.
Solvent Compatibility: Optimal performance in THF/DMF at 60-80°C.
Catalytic Systems: Palladium catalysts recommended for cross-coupling reactions.
Case 1: European Pharma Company (2023)
- Application: Synthesis of BTK inhibitor candidates
- Results: 22% yield improvement vs. traditional intermediates
Case 2: Asian Agrochemical Producer (2024)
- Application: Fungicide intermediate scale-up
- Outcome: Reduced production costs by 15%
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