Parameter | 3-Amino-4-iodopyridine | Analogous Compounds |
---|---|---|
CAS Number | 1072-98-6 | N/A |
Molecular Formula | C5H5IN2 | C5H5BrN2 (3-Bromo variant) |
Purity Grade | ≥98% (HPLC) | 95-97% (Standard) |
Storage Conditions | 2-8°C, inert atmosphere | Room temperature (Analog) |
Pharmaceutical Intermediate: Critical precursor for kinase inhibitor development in oncology therapeutics
Organic Synthesis: Versatile building block for cross-coupling reactions (Suzuki, Buchwald-Hartwig)
Material Science: Key component in conductive polymer research and OLED development
Solubility Profile:
- Polar solvents: DMF, DMSO (20-50 mg/mL)
- Non-polar solvents: Limited solubility (<5 mg/mL)
Reactivity Advisory:
- Air-sensitive in solution phase
- Light-induced decomposition observed beyond 72hr exposure
Case A: Pharmaceutical Intermediate Scale-Up
- Application: EGFR inhibitor precursor synthesis
- Scale: 50kg batch production
- Yield Improvement: 22% vs traditional routes
Client 1: European CRO (Contract Research Organization)
- Application: Library compound synthesis for high-throughput screening
- Consumption: 15kg/quarter (2023-2024)
- Feedback: "Consistent purity enabled 92% reaction success rate"
Client 2: Asian API Manufacturer
- Usage: Intermediate in tyrosine kinase inhibitor production
- Annual Procurement: 300kg (2024 forecast)
- Certification: Passed stringent ICH Q7 audits
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