2,5-Dibromo-3-nitropyridine

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Table of Contents

1. Product Overview & Specifications

2,5-Dibromo-3-nitropyridine Technical Parameters

Parameter Specification
CAS Number 374545-67-8
Molecular Formula C5H2Br2N2O2
Molecular Weight 306.89 g/mol
Appearance Yellow crystalline powder
Purity (HPLC) ≥98.5%
Melting Point 92-95°C

Comparative Analysis with Similar Derivatives

Compound Reactivity Cost Efficiency Typical Yield
2,5-Dibromo-3-nitropyridine High Medium 85-92%
2,3-Dibromo-5-nitropyridine Moderate High 78-85%
2-Chloro-5-nitropyridine Low Low 90-95%

2. Key Applications & Industrial Uses

Pharmaceutical Intermediate

Critical precursor for kinase inhibitors and antiviral agents with enhanced bromine-mediated coupling efficiency.

Agrochemical Synthesis

Essential component in next-generation fungicides requiring dual halogen functionality.

Material Science

Building block for conductive polymers in OLED applications (λmax 420-450 nm range).

3. Application Scenarios in Organic Synthesis

Suzuki Cross-Coupling Reactions

Demonstrated reaction efficiency with arylboronic acids (Pd(PPh3)4 catalyst, 80°C, 12h).

Nucleophilic Aromatic Substitution

Selective displacement of bromine atoms at C2 position with amine nucleophiles.

4. Industrial Case Studies

Antiviral Drug Development

Used in 7-step synthesis of NS5A inhibitor candidates (patent WO2021156478A1).

OLED Material Production

Key intermediate in electron-transport layer materials achieving 18% external quantum efficiency.

5. Verified Client Implementations

PharmaCorp Solutions

Challenge: Required high-purity intermediate for GLP-1 receptor agonist development.
Solution: Custom synthesis with >99% purity
Result: Accelerated preclinical studies by 40%

AgroTech Innovations

Challenge: Develop broad-spectrum fungicide with reduced environmental impact
Solution: Optimized bromine substitution pattern
Result: Achieved 92% disease suppression in field trials

6. Request Technical Documentation

Contact our technical team for:
– COA samples
– Custom synthesis protocols
– Regulatory support documents
Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Our Product?

  • Batch-to-batch consistency (RSD <1.5%)
  • GMP-compliant manufacturing
  • 50kg+ bulk order capabilities
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