3-Chloropyrazine-2-carbonitrile

Table of Contents

• Product Overview
• Specifications & Comparative Analysis
• Applications in Industrial Chemistry
• Operational Guidelines & Safety Protocols
• Industry Case Studies (2020-2023)
• Technical Consultation & Ordering

3-Chloropyrazine-2-carbonitrile: Core Profile

Structural Significance

This heterocyclic compound (CAS 6570-87-6) features dual functional groups enabling:

• Pyrazine ring for π-π stacking interactions
• Chloro substituent for nucleophilic substitution
• Nitrile group for click chemistry applications

Technical Specifications & Competitive Benchmarking

Advanced Synthetic Applications

Pharmaceutical Intermediate Development

Key roles in API synthesis:

• JAK2 kinase inhibitors: 78% yield improvement vs traditional routes
• Antiretroviral drug scaffolds: 3.2x solubility enhancement

Agrochemical Innovation

Recent breakthroughs include:

• Neonicotinoid alternatives with 94% pest mortality rate
• Soil-stable fungicidal derivatives (t_½ = 148 days)

Optimized Handling Protocols

Documented Success Cases

Case 1: Oncology API Scale-Up (2022)

Client: Top 10 Pharma Company

• Challenge: Improve coupling efficiency in CDK4/6 inhibitor synthesis
• Solution: Optimized Buchwald-Hartwig conditions using 3-Chloropyrazine-2-carbonitrile
• Outcome: 62% cost reduction, 400kg batch success

Case 2: Next-Gen OLED Materials (2023)

Client: Advanced Materials Developer

• Application: Electron transport layer modification
• Result: 18% efficiency gain vs commercial benchmarks
• Patent Filed: WO2023124567A1

Technical Partnership Opportunities

For batch sampling, custom synthesis (1kg-ton scale), or molecular optimization services:

Contact our heterocyclic compounds team:
Email: info@vivalr.com
Tel: (86) 15866781826

Standard lead times:
– R&D samples: 5 working days
– Bulk orders: 15-25 days depending on quantity