2-Chloro-4-(trifluoromethyl)pyrimidine

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2-Chloro-4-(trifluoromethyl)pyrimidine: Technical Guide for Industrial Buyers & Researchers

Table of Contents

Product Specifications & Comparative Analysis

Parameter Specification Competitor A Competitor B
CAS Number 849924-75-8 849924-75-8 849924-75-8
Purity ≥99.5% (HPLC) ≥98% ≥97%
Storage Conditions 2-8°C in inert gas Ambient 4-10°C

Industrial Applications & Functional Mechanisms

This heterocyclic compound serves as critical building block in:

  • Kinase inhibitor development (EGFR/VEGFR applications)
  • Non-nucleoside reverse transcriptase inhibitors
  • Fluorinated pesticide intermediates
  • OLED material precursors

Operational Protocols & Safety Guidelines

Parameter Requirement
Reaction Solvent Compatibility DCM, THF, DMF (anhydrous conditions)
Temperature Range -20°C to 120°C (controlled environments)

Case Study 1: Anticancer Drug Intermediate Synthesis

Client: Top 10 Global Pharma Company (Confidential)

  • Application: Third-generation EGFR inhibitor development
  • Scale: 200kg pilot batch production
  • Result: 92% yield improvement vs previous synthon

Case Study 2: Novel Insecticide Development

Client: EU Agrochemical Manufacturer

  • Application: Fluorinated pest control agent
  • Process: Suzuki coupling optimization
  • Outcome: Reduced byproducts by 40%

Material Science Application Example

Client: Advanced Materials Research Institute

  • Usage: Electron transport layer precursor
  • Performance: Achieved 18% OLED efficiency
  • Purity Requirement: 99.99% (GC-MS verified)

Supplier Qualification Checklist

Evaluation Factor Industry Standard
Batch-to-Batch Consistency ≤0.3% variance (HPLC)
Heavy Metal Content <5ppm (ICP-MS)

Request Technical Consultation

Contact our chemistry experts for:

  • Custom synthesis protocols
  • Regulatory compliance documentation
  • Bulk order pricing (100kg+ quantities)

Email: info@vivalr.com
Tel: (86) 15866781826

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