2-Bromo-5-phenylthiophene: Ultimate User Guide

Table of Contents

Product Specifications

Parameter Value
Chemical Formula C10H7BrS
CAS Number 102113-98-4
Molecular Weight 239.13 g/mol
Appearance Off-white crystalline powder
Purity >98% (HPLC)
Melting Point 78-82°C
Storage 2-8°C in airtight container

Key Applications

Pharmaceutical Intermediates

Critical building block for kinase inhibitors and anticancer agents. Enables precise bromine-directed cross-coupling reactions.

Organic Electronics

Essential monomer for conjugated polymers in OLEDs and OFETs. Enhances charge transport properties through thiophene ring modification.

Agrochemical Synthesis

Used in development of advanced fungicides with improved environmental stability.

Usage Scenarios

Case 1: Suzuki-Miyaura Coupling

Typical reaction conditions:
– Catalyst: Pd(PPh3)4 (2 mol%)
– Base: K2CO3 (2 eq)
– Solvent: THF/H2O (3:1)
Yield: 85-92% after purification

Case 2: Polymer Synthesis

Stille polycondensation with distannylated comonomers produces materials with:
– Bandgap: 2.1-2.3 eV
– Hole mobility: 10-3 cm²/V·s

Technical Comparison

Property 2-Bromo-5-phenylthiophene 2-Bromo-thiophene 5-Phenylthiophene
Reactivity High (dual functionalization) Moderate Low
Thermal Stability Up to 200°C 180°C 220°C
Solubility THF, DCM, DMF Ether, THF Toluene

Client Success Stories

PharmaTech Solutions

Challenge: Needed high-purity intermediate for Phase III clinical trial material
Solution: Custom synthesis at 99.5% purity with strict particle size control
Result: Achieved 40% yield improvement vs previous supplier

MaterialScience Inc.

Application: Developing flexible OLED displays
Outcome: Created polymer with 18% higher luminous efficiency
Volume: 50kg/month contract for R&D scale production

Request Custom Solutions

Our advantages:
– Batch-to-batch consistency (RSD <0.8%)
– Technical support from PhD chemists
– Global logistics compliance

Contact our team:
Email: info@vivalr.com
Tel: (86) 15866781826

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