2-Amino-3-cyanopyridine

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2-Amino-3-cyanopyridine: Comprehensive User Guide for Industrial and Research Applications

1. Product Overview and Specifications

Chemical Profile

2-Amino-3-cyanopyridine (CAS 14332-41-3) is a versatile heterocyclic compound with molecular formula C6H5N3 and molecular weight 119.13 g/mol. This yellow crystalline powder boasts ≥98% purity (HPLC) and exceptional thermal stability (decomposition point: 215°C).

Comparative Analysis

Parameter 2-Amino-3-cyanopyridine 2-Amino-4-cyanopyridine 3-Amino-2-cyanopyridine
Molecular Formula C6H5N3 C6H5N3 C6H5N3
Melting Point 215°C (dec.) 198-202°C 185-190°C
Pharma Applications High Moderate Low

2. Key Applications and Use Cases

Pharmaceutical Intermediates

Critical for synthesizing:

  • Tyrosine kinase inhibitors (e.g., anti-cancer agents)
  • Antiviral compound backbones
  • Neurological drug precursors

Agrochemical Development

Enables creation of:

  • Next-gen neonicotinoid alternatives
  • Fungicidal pyridine derivatives

3. Step-by-Step Usage Guidelines

Synthetic Protocol

  1. Weigh under inert atmosphere (N2/Ar)
  2. Dissolve in anhydrous DMF (1:5 w/v ratio)
  3. Maintain reaction at 80-85°C for 4-6 hours

Safety Protocols

Parameter Requirement
PPE Class III gloves, face shield
Ventilation Fume hood with ≥100 CFM airflow

4. Industry Case Studies

Case 1: Pharma Intermediate Scale-Up

Client: EuroPharma Solutions (Germany)

  • Challenge: Achieve 98.5% purity at 500kg batch scale
  • Solution: Optimized crystallization protocol
  • Result: 99.2% purity with 87% yield

Case 2: Agrochemical Formulation

Client: AgroNova Ltd. (Brazil)

  • Challenge: Develop temperature-stable insecticide
  • Solution: Modified pyridine side chains
  • Result: 40% efficacy improvement at 40°C

5. Contact for Custom Solutions

Request bulk pricing or technical specs:

Why Choose Us:

  • ISO 9001-certified production
  • Custom particle size distributions (10-200µm)
  • GMP-grade batches available

Note: Always consult MSDS before use. Data provided for informational purposes only.

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