2-Amino-3-cyanopyridine: Comprehensive User Guide for Industrial and Research Applications
Table of Contents
1. Product Overview and Specifications
Chemical Profile
2-Amino-3-cyanopyridine (CAS 14332-41-3) is a versatile heterocyclic compound with molecular formula C6H5N3 and molecular weight 119.13 g/mol. This yellow crystalline powder boasts ≥98% purity (HPLC) and exceptional thermal stability (decomposition point: 215°C).
Comparative Analysis
| Parameter | 2-Amino-3-cyanopyridine | 2-Amino-4-cyanopyridine | 3-Amino-2-cyanopyridine |
|---|---|---|---|
| Molecular Formula | C6H5N3 | C6H5N3 | C6H5N3 |
| Melting Point | 215°C (dec.) | 198-202°C | 185-190°C |
| Pharma Applications | High | Moderate | Low |
2. Key Applications and Use Cases
Pharmaceutical Intermediates
Critical for synthesizing:
- Tyrosine kinase inhibitors (e.g., anti-cancer agents)
- Antiviral compound backbones
- Neurological drug precursors
Agrochemical Development
Enables creation of:
- Next-gen neonicotinoid alternatives
- Fungicidal pyridine derivatives
3. Step-by-Step Usage Guidelines
Synthetic Protocol
- Weigh under inert atmosphere (N2/Ar)
- Dissolve in anhydrous DMF (1:5 w/v ratio)
- Maintain reaction at 80-85°C for 4-6 hours
Safety Protocols
| Parameter | Requirement |
|---|---|
| PPE | Class III gloves, face shield |
| Ventilation | Fume hood with ≥100 CFM airflow |
4. Industry Case Studies
Case 1: Pharma Intermediate Scale-Up
Client: EuroPharma Solutions (Germany)
- Challenge: Achieve 98.5% purity at 500kg batch scale
- Solution: Optimized crystallization protocol
- Result: 99.2% purity with 87% yield
Case 2: Agrochemical Formulation
Client: AgroNova Ltd. (Brazil)
- Challenge: Develop temperature-stable insecticide
- Solution: Modified pyridine side chains
- Result: 40% efficacy improvement at 40°C
5. Contact for Custom Solutions
Request bulk pricing or technical specs:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Why Choose Us:
- ISO 9001-certified production
- Custom particle size distributions (10-200µm)
- GMP-grade batches available
Note: Always consult MSDS before use. Data provided for informational purposes only.
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