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2-Amino-3-cyanopyridine: Comprehensive User Guide for Industrial and Research Applications

Table of Contents

1. Product Overview and Specifications

Chemical Profile

2-Amino-3-cyanopyridine (CAS 14332-41-3) is a versatile heterocyclic compound with molecular formula C6H5N3 and molecular weight 119.13 g/mol. This yellow crystalline powder boasts ≥98% purity (HPLC) and exceptional thermal stability (decomposition point: 215°C).

Comparative Analysis

Parameter 2-Amino-3-cyanopyridine 2-Amino-4-cyanopyridine 3-Amino-2-cyanopyridine
Molecular Formula C6H5N3 C6H5N3 C6H5N3
Melting Point 215°C (dec.) 198-202°C 185-190°C
Pharma Applications High Moderate Low

2. Key Applications and Use Cases

Pharmaceutical Intermediates

Critical for synthesizing:

  • Tyrosine kinase inhibitors (e.g., anti-cancer agents)
  • Antiviral compound backbones
  • Neurological drug precursors

Agrochemical Development

Enables creation of:

  • Next-gen neonicotinoid alternatives
  • Fungicidal pyridine derivatives

3. Step-by-Step Usage Guidelines

Synthetic Protocol

  1. Weigh under inert atmosphere (N2/Ar)
  2. Dissolve in anhydrous DMF (1:5 w/v ratio)
  3. Maintain reaction at 80-85°C for 4-6 hours

Safety Protocols

Parameter Requirement
PPE Class III gloves, face shield
Ventilation Fume hood with ≥100 CFM airflow

4. Industry Case Studies

Case 1: Pharma Intermediate Scale-Up

Client: EuroPharma Solutions (Germany)

  • Challenge: Achieve 98.5% purity at 500kg batch scale
  • Solution: Optimized crystallization protocol
  • Result: 99.2% purity with 87% yield

Case 2: Agrochemical Formulation

Client: AgroNova Ltd. (Brazil)

  • Challenge: Develop temperature-stable insecticide
  • Solution: Modified pyridine side chains
  • Result: 40% efficacy improvement at 40°C

5. Contact for Custom Solutions

Request bulk pricing or technical specs:

Why Choose Us:

  • ISO 9001-certified production
  • Custom particle size distributions (10-200µm)
  • GMP-grade batches available

Note: Always consult MSDS before use. Data provided for informational purposes only.

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Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
5000+ square meters R&D center
A 70+ R&D team led by Chinese and foreign doctors
150 pieces (sets) of R&D equipment, 120+ fume hoods
18 patents

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
It has successfully passed on-site inspections from the United States, Australia, Poland, Japan and domestic pharmaceutical company customers and institutions many times, providing high-quality one-stop services for R&D and production of new drugs around the world.

More than 150 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

About the company

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FAQ

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Delivery time

Under normal circumstances, all items are in stock and will be shipped before 4 o'clock on the same day. Some products are produced to order, depending on the workshop situation and production schedule.

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At present, the company's workshop production equipment is mainly based on laboratories and pilot lines, with a maximum daily production capacity of 1.5 tons.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Chem-iso’s delivery rate is guaranteed to be 99.99%

5000+

square meter R&D center

150+

China(set) of R&D equipment

150+

Fume hood

180+

R&D team

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