4-BroMo-6-chloropyridazin-3(2H)-one CAS 933041-13-5

4-Bromo-6-chloropyridazin-3(2H)-one CAS 933041-13-5: Ultimate Guide

Table of Contents

• Product Overview & Specifications
• Key Applications & Industrial Uses
• Technical Comparison with Analogues
• Synthesis & Handling Protocols
• Customer Case Studies
• Procurement Guidance

1. Product Specifications

Comparative Analysis

2. Industrial Applications

Pharmaceutical Intermediates

Essential for synthesizing kinase inhibitors in oncology research, particularly in Bruton’s tyrosine kinase (BTK) inhibitor development.

Agrochemical Synthesis

Used as precursor in next-generation fungicides with enhanced environmental persistence.

3. Technical Comparison

Compared to 4-iodo derivatives, bromo substitution offers better cost efficiency while maintaining sufficient reactivity for Suzuki couplings.

4. Synthesis Protocol

Typical reaction sequence:

1. Chloropyridazinone bromination using NBS
2. Selective deprotection at position 6
3. Crystallization from ethanol/water

5. Customer Case Studies

Case 1: Oncology Research Institute

Used 25kg batch in BTK inhibitor optimization, achieving 92% coupling efficiency in palladium-catalyzed reactions.

Case 2: Agrochemical Manufacturer

Developed novel fungicide with 40% improved field performance using our material as key intermediate.

6. Procurement Assistance

Our GMP-compliant production ensures:

• Lot-to-lot consistency
• Custom packaging (1kg-100kg)
• Regulatory documentation support

Contact our technical team:

Email: info@vivalr.com
Tel: (86) 15866781826