5-Methyluridine CAS 1463-10-1

5-Methyluridine CAS 1463-10-1: Ultimate Product Guide

Table of Contents

• 1. Product Specifications & Comparative Analysis
• 2. Key Applications & Industrial Uses
• 3. Operational Best Practices
• 4. Verified Client Case Studies
• 5. Technical Consultation & Quotation

1. Product Specifications & Comparative Analysis

2. Key Applications & Industrial Uses

RNA Modification Studies: Essential for investigating post-transcriptional RNA modifications in epigenetic regulation.

Antiviral Drug Development: Serves as precursor compound in nucleotide analog synthesis for HCV/HIV inhibitors.

Diagnostic Probe Design: Enables creation of methylation-specific molecular probes for disease biomarkers.

3. Operational Best Practices

Solubility Management: Dissolve in DEPC-treated water (50 mg/mL) with brief warming to 37°C

Reaction Optimization: Maintain pH 7.0-7.4 in enzymatic systems using phosphate buffers

QC Validation: Verify identity through LC-MS (ESI+) with expected m/z 259.09 [M+H]+

4. Verified Client Case Studies

Case 1: European Pharma Research Consortium

Challenge: Required ultra-pure methylated nucleosides for nucleotide analog library synthesis

Solution: Supplied 500g batch with 99.2% purity (HPLC-UV/DAD)

Outcome: Achieved 92% coupling efficiency in solid-phase oligonucleotide synthesis

Case 2: US Biotech Startup (mRNA Therapeutics)

Challenge: Needed GMP-grade material for IVT template optimization

Solution: Custom synthesis with endotoxin levels <0.1 EU/mg

Outcome: Enhanced mRNA translation efficiency by 40% in in vivo models

5. Technical Consultation & Quotation

Request product specifications sheet or discuss bulk order requirements:

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