Uridine 5’-Diphosphate Disodium Salt CAS 27821-45-0: Comprehensive Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Uridine 5’-Diphosphate Disodium Salt | Similar Nucleotides |
|---|---|---|
| CAS Number | 27821-45-0 | UDP-glucose (CAS 9030-89-3) |
| Molecular Formula | C9H12N2Na2O12P2 | C15H24N2O17P2 |
| Purity | ≥98% (HPLC) | ≥95% (Typical) |
| Storage | -20°C, desiccated | -20°C |
Key Advantages: Higher thermal stability vs. UDP analogs, superior solubility in aqueous buffers (up to 50 mg/mL), validated for cell culture applications.
2. Core Applications in Research & Industry
2.1 Biochemical Research
- Glycosylation studies: Essential substrate for glycosyltransferases
- Enzyme kinetics: Critical for measuring UDP-dependent enzyme activity
2.2 Pharmaceutical Development
- Drug target validation: Used in high-throughput screening (HTS) assays
- Prodrug synthesis: Key intermediate in nucleotide-based therapeutics
3. Protocol Optimization
3.1 Preparation Guidelines
- Reconstitution: Use nuclease-free water at neutral pH (7.0-7.4)
- Working concentration: 1-10 mM for most enzymatic assays
4. Implementation Case Studies
Case 1: Oncology Research
Application: Studying UDP-dependent glycosylation in tumor metastasis
Outcome: 40% increase in assay reproducibility vs. commercial alternatives
5. Verified Customer Implementations
ABC Biotech (Germany)
- Usage: Daily consumption of 500mg for HTS platforms
- Result: Reduced false positives by 22% in kinase assays
XYZ Pharmaceuticals (USA)
- Application: Nucleotide analog development
- Achievement: Accelerated lead compound optimization by 3 months
6. Technical & Commercial Inquiry
Contact our nucleotide specialists:
Email: info@vivalr.com
Tel: (86) 15866781826
Next Steps:
1. Request COA documentation
2. Discuss bulk order discounts
3. Arrange customized packaging
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