1,2-distearoyl-sn-glycero-3-phosphocholine CAS 816-94-4

Chemical Name: 1,2-distearoyl-sn-glycero-3-phosphocholine
CAS No.: 816-94-4
Molecular Fomula: C44H88NO8P
Molecular weight: 790.15
Appearance: white powder
Assay: 99%min

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1,2-Distearoyl-sn-glycero-3-phosphocholine (DSPC) CAS 816-94-4: Comprehensive User Guide

Table of Contents

1. Product Overview

1,2-Distearoyl-sn-glycero-3-phosphocholine (DSPC), CAS 816-94-4, is a synthetic saturated phospholipid widely used in pharmaceutical formulations, liposomal drug delivery systems, and biomedical research. Its high phase transition temperature (~55°C) and chemical stability make it ideal for controlled-release applications.

2. Specifications & Comparative Analysis

Parameter DSPC DOPC POPC
CAS Number 816-94-4 4235-95-4 32443-39-3
Phase Transition Temp. 55°C -20°C -2°C
Fatty Acid Chains C18:0 (Saturated) C18:1 (Unsaturated) C16:0-C18:1

3. Key Applications

3.1 Drug Delivery Systems

DSPC is critical in formulating temperature-stable liposomes for anticancer drugs (e.g., Doxorubicin) and mRNA vaccines due to its bilayer rigidity.

3.2 Diagnostic Reagents

Used as stabilizing agents in IVD kits for biomarker encapsulation and signal amplification.

4. Use Cases & Client Examples

4.1 Case Study 1: Oncology Therapeutics

Client: Top 10 Pharma Company (USA)
Application: DSPC-based liposomes for prolonged circulation of Paclitaxel, achieving 40% tumor reduction in preclinical models.

4.2 Case Study 2: Vaccine Development

Client: European Biotech Startup
Application: Utilized DSPC in self-amplifying RNA vaccine formulations, enhancing thermostability from 4°C to 25°C storage.

5. Contact for Custom Solutions

Email: info@vivalr.com
Phone: (86) 15866781826

Request tailored DSPC solutions with:

  • GMP-grade manufacturing
  • Batch-specific COA
  • Technical support for formulation optimization
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