Chemical Name: 1,2-distearoyl-sn-glycero-3-phosphocholine
CAS No.: 816-94-4
Molecular Fomula: C44H88NO8P
Molecular weight: 790.15
Appearance: white powder
Assay: 99%min
1,2-Distearoyl-sn-glycero-3-phosphocholine (DSPC), CAS 816-94-4, is a synthetic saturated phospholipid widely used in pharmaceutical formulations, liposomal drug delivery systems, and biomedical research. Its high phase transition temperature (~55°C) and chemical stability make it ideal for controlled-release applications.
Parameter | DSPC | DOPC | POPC |
---|---|---|---|
CAS Number | 816-94-4 | 4235-95-4 | 32443-39-3 |
Phase Transition Temp. | 55°C | -20°C | -2°C |
Fatty Acid Chains | C18:0 (Saturated) | C18:1 (Unsaturated) | C16:0-C18:1 |
DSPC is critical in formulating temperature-stable liposomes for anticancer drugs (e.g., Doxorubicin) and mRNA vaccines due to its bilayer rigidity.
Used as stabilizing agents in IVD kits for biomarker encapsulation and signal amplification.
Client: Top 10 Pharma Company (USA)
Application: DSPC-based liposomes for prolonged circulation of Paclitaxel, achieving 40% tumor reduction in preclinical models.
Client: European Biotech Startup
Application: Utilized DSPC in self-amplifying RNA vaccine formulations, enhancing thermostability from 4°C to 25°C storage.
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