Bis(dibenzylideneacetone)palladium Cas 32005-36-0

Chemical Name: Bis(dibenzylideneacetone)palladium
CAS No.: 32005-36-0
Molecular Fomula: C34H20O2Pd

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Bis(dibenzylideneacetone)palladium (CAS 32005-36-0) Comprehensive Guide 2025

Table of Contents

Product Overview & Specifications

Parameter Specification
CAS Number 32005-36-0
Molecular Formula C34H28O2Pd
Appearance Dark red crystalline powder
Purity ≥99% (HPLC)
Storage Conditions 2-8°C in inert atmosphere

Key Applications & Industrial Uses

Primary applications in organic synthesis:

  • Suzuki-Miyaura cross-coupling reactions
  • Buchwald-Hartwig amination reactions
  • Heck coupling for C-C bond formation
  • Pharmaceutical intermediate synthesis

Performance Comparison With Alternative Catalysts

Catalyst Reaction Yield Air Stability Typical Loading
Pd(dba)2 92-98% Moderate 0.5-2 mol%
Pd(PPh3)4 85-90% Low 1-5 mol%
PdCl2 75-88% High 5-10 mol%

Step-by-Step Usage Protocols

Standard reaction setup:

  1. Charge reactor with aryl halide (1.0 equiv)
  2. Add boronic acid (1.2 equiv)
  3. Dissolve Pd(dba)2 in degassed solvent (0.8 mol%)
  4. Maintain reaction at 80°C under N2 for 12-18hr

Real-World Case Studies

Case 1: Anticancer Drug Intermediate Synthesis

Client: Top 10 Pharma Company (Germany)

  • Application: Synthesis of PD-1/PD-L1 inhibitor intermediates
  • Result: 94% yield improvement vs previous catalyst

Case 2: OLED Material Production

Client: OLED Materials Manufacturer (South Korea)

  • Application: Electron transport layer synthesis
  • Result: 40% reduction in metallic residues

Technical Consultation & Ordering

Contact our catalysis specialists:

Email: info@vivalr.com
Tel: (86) 15866781826

Request:

  • Custom particle size distributions
  • GMP-grade manufacturing
  • Bulk pricing (25kg+ orders)
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