Prop-1-ene-1,3-sultone CAS 21806-61-1

Chemical Name: Prop-1-ene-1,3-sultone
CAS No.: 21806-61-1
Molecular Fomula: C3H4O3S
Molecular weight: 120.13
Appearance: White to off-white solid
Assay: 98%

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Table of Contents

Prop-1-ene-1,3-sultone (CAS 21806-61-1) Overview

Technical Specifications

Parameter Specification
CAS Number 21806-61-1
Molecular Formula C3H4O3S
Molecular Weight 120.13 g/mol
Appearance White crystalline powder
Purity ≥99% (HPLC)
Melting Point 89-92°C
Storage Conditions 2-8°C in dry atmosphere

Comparative Analysis

Feature Prop-1-ene-1,3-sultone Similar Compounds
Thermal Stability Stable up to 150°C Decomposes at 100°C
Reactivity High electrophilic character Moderate reactivity
Solubility DMSO, DMF, THF Limited solvent compatibility

Industrial Applications

Pharmaceutical Intermediates

Used in synthesis of sulfonamide-based APIs for antibacterial medications.

Organic Synthesis

Key reagent in cycloaddition reactions and ring-opening polymerizations.

Polymer Modification

Enhances thermal stability in specialty polymer production.

Operational Guidelines

Handling Protocols

Use under inert gas (N2/Ar) with proper PPE including nitrile gloves and safety goggles.

Reaction Optimization

Optimal reaction conditions: 60-80°C in anhydrous DMF with 1.2eq stoichiometry.

Implementation Case Studies

Case Study 1: Pharmaceutical Manufacturer

Client: Top 10 Global Pharma Company
Application: Synthesis of next-gen sulfa drugs
Result: 23% yield improvement vs traditional methods

Case Study 2: Advanced Materials Lab

Client: National Research Institute
Application: Conductive polymer development
Result: Achieved 15% higher thermal stability

Case Study 3: Electronic Chemicals Producer

Client: Semiconductor Material Supplier
Application: Photoresist component
Result: 40nm resolution improvement

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