1,3-Diphenyl-2-thiourea CAS 102-08-9

Chemical Name: 1,3-Diphenyl-2-thiourea
Synonyms: Thiocarbanilide; N,N’-Diphenylthiourea; sym-Diphenylthiourea
CAS No.: 102-08-9
Molecular Fomula: C13H12N2S
Molecular weight: 228.31
Appearance: Gray white powdery crystal
Assay: ≥99.0%

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1. Product Overview: 1,3-Diphenyl-2-thiourea (CAS 102-08-9)

Synonyms: N,N’-Diphenylthiourea, DPTU
Molecular Formula: C13H12N2S
Molar Mass: 228.31 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
Storage: 2-8°C in airtight container

2. Key Parameters & Comparative Analysis

Parameter 1,3-Diphenyl-2-thiourea Thiourea 1-Phenyl-2-thiourea
Melting Point 154-156°C 176-178°C 142-144°C
Solubility in DMF High (>50 mg/mL) Moderate High
Catalytic Efficiency ★★★★☆ ★★☆☆☆ ★★★☆☆

3. Industrial Applications

3.1 Organic Synthesis

  • Key intermediate for heterocyclic compounds (e.g., thiazoles)
  • Catalyst in Biginelli reactions

3.2 Pharmaceutical Manufacturing

  • Building block for antiviral agents
  • Intermediate in anticonvulsant drug synthesis

4. Usage Scenarios & Mechanisms

4.1 Case A: Catalytic Application

Scenario: Synthesis of dihydropyrimidinones
Mechanism: Acts as hydrogen bond donor in solvent-free conditions
Result: 92% yield improvement vs. conventional catalysts

4.2 Case B: Rubber Additive

Scenario: Vulcanization accelerator in NBR
Mechanism: Reduces activation energy by 15-20%
Result: 30% faster processing time

5. Client Case Studies

5.1 ABC Pharmaceuticals (Germany)

  • Application: Intermediate for neurology drugs
  • Consumption: 500 kg/month
  • Outcome: Reduced synthesis steps from 5 to 3

5.2 XYZ Chemical Solutions (USA)

  • Application: Corrosion inhibitor formulation
  • Result: 40% improvement in metal protection

6. Request a Quote or Technical Consultation

Contact our chemical experts for:
– Custom synthesis specifications
– Bulk pricing (100kg+ orders)
– Regulatory documentation support

Email: info@vivalr.com
Tel: (86) 15866781826

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✓ ISO 9001-certified production
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