Balsalazide disodium CAS 150399-21-6

Balsalazide Disodium (CAS 150399-21-6) Technical Guide

Table of Contents

• 1. Product Specifications & Comparative Analysis
• 2. Therapeutic Applications & Mechanisms
• 3. Pharmaceutical Formulation Guidance
• 4. Industry Application Scenarios
• 5. Verified Client Implementations
• 6. Technical Consultation & Procurement

1. Product Specifications & Comparative Analysis

2. Therapeutic Applications & Mechanisms

Primary Indications:
– Ulcerative colitis maintenance therapy
– Active Crohn’s disease management
– Radiation proctitis treatment

Pharmacological Action:
Prodrug conversion to 5-aminosalicylic acid (5-ASA) in colon:
1. Targeted anti-inflammatory action
2. Reduced systemic absorption
3. Enhanced mucosal healing

3. Pharmaceutical Formulation Guidance

Stability Parameters:
– Storage: 2-8°C protected from light
– Solubility: ≥50 mg/mL in aqueous solutions
– pH Stability Range: 7.0-9.0

Manufacturing Considerations:
– Microwave-assisted synthesis optimization
– Heavy metal control: ≤50 ppm
– Residual solvent management

4. Industry Application Scenarios

Clinical Applications:
– First-line therapy for mild-moderate UC
– Steroid-sparing agent in maintenance phases
– Combination therapy with biologics

Research Applications:
– Inflammatory bowel disease models
– Colorectal cancer prevention studies
– Mucosal healing biomarkers research

5. Verified Client Implementations

Case Study 1: Major Pharma Producer
– Application: GMP-grade API production
– Scale: 500kg/month output
– Purity: 99.8% by HPLC

Case Study 2: Research Institute
– Application: Novel drug delivery systems
– Achievement: 40% bioavailability improvement
– Duration: 18-month study period

6. Technical Consultation & Procurement

For technical specifications, COA, or bulk pricing:
Contact:
– Email: info@vivalr.com
– Tel: (86) 15866781826

Procurement Options:
– Sample quantities: 1g-100g
– Clinical trial batches: 1kg-10kg
– Commercial quantities: 25kg+