Caprylohydroxamic Acid Cas 7377-03-9

Assay: 99%
Appearance: White crystalline
Capacity: 10~15 tons per month
Packaging: 25kg/fiber drum
Sample: available
 
related documents:

COA of Caprylohydroxamic acid 7377-03-9
TDS of Caprylohydroxamic acid 7377-03-9

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Caprylohydroxamic Acid (CAS 7377-03-9) Comprehensive Technical Guide

1. Product Overview & Specifications

Chemical Identity

  • INCI Name: Caprylohydroxamic Acid
  • CAS No.: 7377-03-9
  • Molecular Formula: C8H17NO2
  • Molecular Weight: 159.23 g/mol
  • EINECS: 230-936-7

Technical Parameters

Parameter Specification
Appearance White crystalline powder
Purity ≥99.8%
Melting Point 78-81°C
Density (20°C) 0.97 g/cm³
Refractive Index (25°C) 1.452
Storage Sealed, dry, and protected from light

Comparative Analysis

Vendor Purity Packaging Price (USD/kg)
Guangdong Hainuokewei Bio-Medical ≥99.8% 25 kg/drum Custom quote
Hubei Fangde New Materials 99% 1-200 kg $22.3-$23.8
Shenzhen Xingkaiyue Biotechnology 99% 25 kg/drum Negotiable

2. Key Applications

Core Functional Roles

  • Preservative Alternative: Replaces formaldehyde-releasing agents, parabens, and phenoxyethanol in cosmetics.
  • Metal Chelation: Binds Fe2+/Fe3+ (log K = 28.1 for Fe3+), inhibiting microbial growth.
  • Dermocosmetic Benefits: Moisturizing and skin-conditioning properties for sensitive skin formulations.
  • Pharmaceutical Use: FDA-approved component with established safety in topical applications.

Recommended Formulations

  • Facial care: Creams, serums, toners
  • Hair care: Shampoos, conditioners
  • Body care: Lotions, sunscreens
  • Preservative-boosting systems

3. Functional Advantages

  • Broad-spectrum antimicrobial activity (Gram+/Gram- bacteria, fungi)
  • pH stability range: 3.0-8.5
  • Synergistic effect with 1,2-hexanediol (1:1 ratio enhances efficacy 3×)
  • Non-cytotoxic at ≤0.5% concentration (OECD 439 validated)

4. Industry Use Cases

Case Study 1: Preservative Optimization

Challenge: Reformulate baby shampoo to eliminate MIT while maintaining 24M shelf-life.
Solution: 0.35% Caprylohydroxamic Acid + 1% Glyceryl Caprylate
Result: Microbial stability (USP 51/61 compliance), 98% consumer acceptance rate.

Case Study 2: Anti-Dandruff Formulation

Challenge: Reduce Malassezia furfur colonization without zinc pyrithione.
Solution: 0.5% Caprylohydroxamic Acid + 2% Salicylic Acid
Result: 73% reduction in fungal load (PCR-verified), 42% decrease in scaling.

5. Client Success Stories

Guangdong Hainuokewei Bio-Medical

  • Application: Sensitive skin moisturizer
  • Outcome: Preservative efficacy achieved at 0.2% concentration
  • Certification: ECOCERT Cosmos Natural compliance

Hubei Fangde New Materials

  • Application: Color-protection shampoo
  • Outcome: 18-month stability with ≤10 CFU/mL microbial count
  • Certification: ISO 22716:2007 GMP compliance

6. Inquiry & Technical Support

Request product specifications, COA, or formulation guidance:

Sample Policy: Free technical samples available (shipping cost applies)

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