1-Hexanol (CAS 111-27-3) Comprehensive Technical Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 1-Hexanol (CAS 111-27-3) | Alternative Alcohols |
|---|---|---|
| Molecular Formula | C6H14O | C3-C8 variations |
| Molecular Weight | 102.17 g/mol | 60.10-130.23 g/mol |
| Boiling Point | 156-157°C | 97-195°C range |
| Flash Point | 60°C (140°F) | 11-93°C range |
| Solubility | 6 g/L in water (25°C) | Variable polar/non-polar solubility |
Key Differentiators: Optimal carbon chain length for surfactant efficiency, FDA-approved food-grade applications (FEMA 2567), and superior thermal stability compared to shorter-chain alcohols.
2. Key Applications & Industrial Uses
Core Functional Areas:
- Chemical Synthesis: Intermediate for plasticizers (e.g., dioctyl phthalate derivatives)
- Surface Engineering: Non-ionic surfactant in metalworking fluids (5-15% concentration)
- Flavor/Fragrance: GRAS-approved coconut/berry flavor enhancer (0.01-0.1% in final products)
- Pharmaceuticals: Co-solvent in transdermal drug delivery systems
Performance Advantages:
- Reduces interfacial tension by 28-35% in multiphase systems
- Enhances reaction yields by 12-18% in esterification processes
- Compatible with borohydride reduction protocols (0.5-2M concentrations)
3. Operational Guidelines & Best Practices
Handling Protocols:
- Storage: Nitrogen-purged containers at 15-25°C
- Safety: NFPA Health Rating 1, Flammability Rating 2
- PPE Requirements: Butyl rubber gloves + vapor respirator above 50°C
Reaction Optimization:
- Hydrogenation: 40-60psi H2 with Raney Ni catalyst
- Esterification: 110-130°C with p-toluenesulfonic acid
- Phase Transfer: 0.1-0.5% in emulsion stabilization
4. Industry-Specific Use Cases
Case A: Specialty Coatings Formulation
Implemented as flow control additive (2-4% w/w) in automotive clearcoats, achieving 15% reduction in orange peel defects.
Case B: Biocatalyst Medium
Used in non-aqueous enzymolysis systems (0.8M concentration) for taxol semi-synthesis, improving conversion rates by 22%.
5. Verified Client Implementations
Client 1: Advanced Materials Producer
- Application: Dielectric fluid additive for high-voltage capacitors
- Result: 30% increase in breakdown voltage stability
- Volume: 8MT/month (99.5% purity)
Client 2: Flavor House
- Application: Tropical flavor matrix enhancement
- Result: 18% improvement in flavor retention
- Specification: FCC-grade batches
6. Technical Consultation & Ordering
Request formulation support or material specifications:
| Contact Method | Details |
|---|---|
| Technical Support | Email: info@vivalr.com |
| Order Inquiries | Phone: (86) 15866781826 |
Quality Assurance: Batch-specific GC-MS reports available upon request. Custom purity grades (95%-99.9%) with ISO 9001-certified manufacturing.



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