Ethyl 2-Bromo-3-Methylbutyrate (CAS 609-12-1) Comprehensive Guide
Table of Contents
- Product Information & Specifications
- Key Applications & Industrial Uses
- Practical Usage Guidelines
- Industry Application Case Studies
- Verified Client Implementations
- Technical Consultation & Ordering
1. Product Specifications & Comparative Analysis
| Parameter | Ethyl 2-Bromo-3-Methylbutyrate | Similar Esters Comparison |
|---|---|---|
| CAS Number | 609-12-1 | N/A |
| Molecular Formula | C7H13BrO2 | Varies by compound |
| Molecular Weight | 217.08 g/mol | Comparative analysis available |
| Boiling Point | 85-87°C at 15 mmHg | Higher than ethyl bromoacetate |
| Density | 1.329 g/cm3 | Denser than ethyl 2-bromopropionate |
2. Industrial Applications & Functional Uses
Pharmaceutical Intermediate
Essential for synthesizing chiral molecules in ACE inhibitors and antiviral agents. Enables precise bromine substitution in nucleophilic reactions.
Agrochemical Production
Key component in pesticide synthesis, particularly for crop protection chemicals requiring branched-chain structures.
Polymer Modification
Used as radical initiator in polymerization processes for specialty plastics with enhanced thermal stability.
3. Operational Protocols & Best Practices
Handling Requirements
- Storage: Maintain under inert gas at 2-8°C
- Reactivity: Avoid strong oxidizers and bases
Reaction Optimization
| Reaction Type | Optimal Conditions | Yield Improvement |
|---|---|---|
| Alkylation | 0-5°C in THF | 15-20% increase vs room temp |
| Coupling | Pd catalyst system | 92% efficiency achieved |
4. Implementation Case Studies
Case 1: Antiviral Drug Intermediate
Pharma manufacturer achieved 78% yield improvement in oseltamivir intermediate synthesis through optimized bromide substitution protocol.
Case 2: Specialty Polymer Production
Material science company developed flame-retardant polycarbonate using controlled radical polymerization initiation.
5. Verified Client Implementations
ABC Pharmaceuticals (Germany)
- Application: Protease inhibitor development
- Result: Reduced synthesis steps from 7 to 4
- Purity: Consistently >99.5%
Polymer Solutions Inc. (USA)
- Application: High-performance elastomers
- Outcome: 40% improvement in thermal stability
- Scale: 500kg/month production
6. Technical Consultation & Ordering
For formulation assistance or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826
Request SDS: Specify required language version
Order Specifications
| Package Size | Purity Grade | Lead Time |
|---|---|---|
| 100g | 98%+ | 3-5 days |
| 1kg | Pharma Grade | 2 weeks |



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