N1-(3-Aminophenyl)acetamide CAS 102-28-3: Comprehensive Product Guide
Table of Contents
1. Product Overview & Key Parameters
| Parameter | N1-(3-Aminophenyl)acetamide | Alternative Compounds |
|---|---|---|
| CAS Number | 102-28-3 | N/A |
| Molecular Formula | C8H10N2O | Varies by structure |
| Purity Grade | ≥99% (HPLC) | Typically 95-98% |
| Melting Point | 162-165°C | 150-160°C (similar derivatives) |
| Solubility | DMSO, Methanol | Limited in polar solvents |
2. Applications in Pharmaceutical Intermediates
Primary Use: Critical intermediate for:
- Local anesthetic synthesis (e.g., Lidocaine derivatives)
- Antidepressant drug development
- Neurological disorder treatment formulations
Mechanism: Amino group enables nucleophilic substitution reactions essential for building complex drug molecules.
3. Industrial Use Cases & Synthesis Workflow
Case Study 1: Lidocaine Intermediate Production
- Reaction with 2,6-dimethylaniline in ethanol
- Acetylation control at 60°C for 4hrs
- Yield improvement from 72% to 89% through optimized catalysis
Case Study 2: Antidepressant API Synthesis
- Pd-mediated coupling with aryl halides
- Multi-step purification process
- Final API purity achieved: 99.8%
4. Client Success Stories
Pharma Company A (Germany)
- Application: Large-scale anesthetic production
- Result: 22% reduction in side products
- Volume: 800kg/month contract
Research Institute B (USA)
- Application: Novel CNS drug development
- Result: Successful IND submission
- Batch consistency: RSD <0.5% across 10 batches
5. Technical Inquiry & Ordering Process
Contact for:
- Custom synthesis specifications
- Bulk pricing (100kg+ orders)
- Regulatory documentation support
Email: info@vivalr.com
Tel: (86) 15866781826
Next-day quotation with:
- Quantity requirements
- Shipping destination
- Quality certification needs



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