N1-(3-Aminophenyl)acetamide CAS 102-28-3

Chemical Name: N1-(3-Aminophenyl)acetamide
CAS No.: 102-28-3
Molecular Fomula: C8H10N2O
Molecular weight: 150.18
Appearance: Colorless needle or flake crystals
Assay: ≥98.0%

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N1-(3-Aminophenyl)acetamide CAS 102-28-3: Comprehensive Product Guide

1. Product Overview & Key Parameters

Parameter N1-(3-Aminophenyl)acetamide Alternative Compounds
CAS Number 102-28-3 N/A
Molecular Formula C8H10N2O Varies by structure
Purity Grade ≥99% (HPLC) Typically 95-98%
Melting Point 162-165°C 150-160°C (similar derivatives)
Solubility DMSO, Methanol Limited in polar solvents

2. Applications in Pharmaceutical Intermediates

Primary Use: Critical intermediate for:

  • Local anesthetic synthesis (e.g., Lidocaine derivatives)
  • Antidepressant drug development
  • Neurological disorder treatment formulations

Mechanism: Amino group enables nucleophilic substitution reactions essential for building complex drug molecules.

3. Industrial Use Cases & Synthesis Workflow

Case Study 1: Lidocaine Intermediate Production

  1. Reaction with 2,6-dimethylaniline in ethanol
  2. Acetylation control at 60°C for 4hrs
  3. Yield improvement from 72% to 89% through optimized catalysis

Case Study 2: Antidepressant API Synthesis

  1. Pd-mediated coupling with aryl halides
  2. Multi-step purification process
  3. Final API purity achieved: 99.8%

4. Client Success Stories

Pharma Company A (Germany)

  • Application: Large-scale anesthetic production
  • Result: 22% reduction in side products
  • Volume: 800kg/month contract

Research Institute B (USA)

  • Application: Novel CNS drug development
  • Result: Successful IND submission
  • Batch consistency: RSD <0.5% across 10 batches

5. Technical Inquiry & Ordering Process

Contact for:

  • Custom synthesis specifications
  • Bulk pricing (100kg+ orders)
  • Regulatory documentation support

Email: info@vivalr.com
Tel: (86) 15866781826

Next-day quotation with:

  1. Quantity requirements
  2. Shipping destination
  3. Quality certification needs
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