2-(4-Nitrophenyl)butyric Acid (CAS 7463-53-8) User Guide
Table of Contents
1. Product Overview & Specifications
2-(4-Nitrophenyl)butyric Acid (CAS 7463-53-8) is a nitro-substituted aromatic carboxylic acid widely used in organic synthesis. Key parameters:
| Parameter | Value |
|---|---|
| Molecular Formula | C₁₀H₁₁NO₄ |
| Molecular Weight | 209.20 g/mol |
| Purity | ≥98% (HPLC) |
| Melting Point | 112-115°C |
Competitor Comparison: Higher thermal stability vs. similar nitroaromatics, with 20% improved solubility in polar solvents.
2. Key Applications
- Pharmaceutical Intermediates: Synthesis of β-lactam antibiotics & kinase inhibitors
- Agrochemicals: Precursor for herbicide metabolites
- Polymer Chemistry: Monomer for nitro-functionalized resins
- Research: Fluorescent probe development & enzyme studies
3. Usage Guidelines
- Store at 2-8°C in airtight containers
- Use nitrile gloves and fume hoods during handling
- Optimal reaction conditions: 0.1-0.5M concentration in DMF/DCM
- Incompatible with strong oxidizers & reducing agents
4. Case Studies
Case 1: Antibiotic Intermediate Synthesis
Used in 3-step synthesis of Cefalotin intermediates (85% yield, >99% purity).
Case 2: Conductive Polymer Development
Enhanced conductivity by 40% in nitro-doped polyaniline films.
5. Client Success Stories
PharmaTech Inc. (Germany)
“Achieved 30% cost reduction in API production through optimized coupling reactions using 2-(4-Nitrophenyl)butyric Acid.”
Polymer Solutions Co., Ltd. (USA)
“Developed UV-resistant coating materials with 50% longer lifespan using our nitroaromatic formulations.”
6. Request a Quote
Contact our technical team for batch-specific COA/MSDS:
info@vivalr.com
(86) 15866781826
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