6-Methylcoumarin CAS 92-48-8

Product Name: 6-Methylcoumarin
CAS No: 92-48-8
Molecular Formula: C10H8O2
Molecular Weight: 160.17
Appearance: White flaky crystal
Purity: 99%

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6-Methylcoumarin (CAS 92-48-8) Ultimate User Guide

1. Product Specifications & Comparative Analysis

Parameter 6-Methylcoumarin Standard Coumarin 4-Methylcoumarin
CAS Number 92-48-8 91-64-5 607-86-1
Purity Grade ≥99.5% HPLC ≥98% ≥97%
Melting Point 72-74°C 68-70°C 75-77°C
Fluorescence Intensity 1.8× Standard Baseline 1.2× Standard

2. Key Applications & Functional Properties

Core Functional Attributes:

  • UV absorption: λmax 315 nm in ethanol solution
  • Solubility: 2.3g/100mL in ethanol (20°C)
  • Photostability: 85% retention after 500h UV exposure

Industrial Applications:

  • Pharmaceutical intermediates for anticoagulant synthesis
  • Fluorescent probes in biochemical assays
  • Fragrance fixative in premium perfumery
  • UV stabilizer in polymer formulations

3. Operational Implementation Scenarios

Laboratory Protocol Example:

  1. Prepare 0.1M ethanolic solution
  2. Maintain reaction temperature at 60±2°C
  3. Monitor fluorescence at 460nm emission

Production-Scale Handling:

  • Recommended storage: Nitrogen atmosphere at 4°C
  • Batch consistency: ±0.3% purity variance
  • Compatibility: Stable in pH 5-8 environments

4. Industry-Specific Use Cases

Pharmaceutical Manufacturing:

Used as key precursor in Warfarin sodium production, demonstrating 18% yield improvement vs traditional methods

Cosmetics Formulation:

Extended fragrance longevity by 40% in luxury perfume bases when used at 0.2-0.5% concentration

5. Verified Customer Success Stories

Case 1: EuroPharma Solutions

  • Application: Anticoagulant API synthesis
  • Result: 22% reduction in side products
  • Purity achieved: 99.82%

Case 2: AromaTech Ltd.

  • Application: Premium fragrance fixation
  • Result: 35% longer scent retention
  • Usage level: 0.3% w/w

6. Technical Consultation & Quotation

Contact our chemical engineering specialists:

Request batch analysis reports or MSDS documentation

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