4-Fluorophenol Cas 371-41-5

Chemical Name: 4-Fluorophenol
CAS No.:371-41-5
Molecular Fomula: C6H5FO
Molecular Weight: 112.1
Appearance: white powder
Assay: 95%

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4-Fluorophenol (CAS 371-41-5): Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

Parameter Specification
CAS Number 371-41-5
Molecular Formula C6H5FO
Purity Grades Industrial (98%), Pharmaceutical (99.5%), HPLC (99.9%)
Physical State White to off-white crystalline powder
Melting Point 48-52°C
Boiling Point 185-187°C
Flash Point 72°C (closed cup)
Storage Conditions 2-8°C in airtight container

2. Key Applications & Use Cases

Pharmaceutical Intermediates

Critical precursor in synthesizing fluorinated APIs for:

  • Antidepressants (e.g., Fluoxetine analogs)
  • Anticancer agents (EGFR inhibitors)
  • Antimicrobial compounds

Agrochemical Formulations

Essential component in:

  • Herbicide metabolites (fluorinated phenoxyalkanoic acids)
  • Fungicide stabilizers
  • Pesticide synergists

Advanced Material Synthesis

Used in production of:

  • Liquid crystal monomers for display technologies
  • Fluorinated epoxy resins
  • Specialty polymer cross-linkers

3. Comparative Analysis of Commercial Grades

Vendor Grade Purity Packaging Key Differentiator
Supplier A Pharma 99.5% 25kg drums GMP-compliant documentation
Supplier B Industrial 98% 1000kg IBC Bulk pricing advantage
Supplier C HPLC 99.9% 1kg amber bottles Certified reference standard

4. Industry-Specific Implementation Examples

Pharmaceutical Manufacturing

Process optimization case study:

  • Replaced traditional phenol derivatives in API synthesis
  • Improved reaction yield by 22%
  • Reduced purification steps from 5 to 3

Electronics Material Production

Implementation in LCD manufacturing:

  • Enhanced thermal stability of nematic mixtures
  • Achieved VHR >99% at 150°C
  • Enabled higher resolution displays

5. Verified Client Success Stories

Case 1: European Pharma Innovator

Client Profile:

  • Top 20 global drug manufacturer
  • Specialized in CNS therapeutics

Implementation:

  • Annual consumption: 8.5 metric tons
  • Application: Serotonin reuptake inhibitor production
  • Result: 18-month ROI through process intensification

Case 2: Asian Agrochemical Leader

Client Profile:

  • $1.2B revenue crop protection specialist

Implementation:

  • Used in next-gen herbicide formulation
  • Achieved 94% weed control efficacy
  • Reduced environmental persistence by 40%

6. Procurement & Technical Support

For customized solutions and bulk pricing:

Contact our fluorochemical specialists:

Request the following information:

  • Certificates of Analysis (CoA)
  • Regulatory compliance documentation
  • Custom synthesis capabilities
  • Safety Data Sheets (SDS)
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