1. Product Overview and Specifications

Chemical Name: Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate

CAS Number: 82692-93-1

Synonyms: TOOS, Sodium N-ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine

Purity: ≥99.0% (HPLC)

Appearance: White crystalline powder

Molecular Formula: C₁₃H₂₀NNaO₄S

Storage: Store in a cool, dry place at 2-8°C

Key Specifications

2. Applications and Key Uses

This compound is widely utilized in biochemical and diagnostic applications:

• Cholesterol Quantification: Critical reagent in colorimetric assays for enzymatic determination of cholesterol levels.
• Catalase Activity Analysis: Water-soluble chromogen for spectrophotometric detection of hydrogen peroxide decomposition.
• Oxidative Stress Research: Used in studies involving reactive oxygen species (ROS) detection systems.

3. Usage Guidelines and Best Practices

Recommended Workflow:

1. Prepare a 50 mg/mL stock solution in deionized water
2. Filter through 0.22 µm membrane for sterility
3. Store aliquots at -20°C for long-term stability
4. Use within 24 hours after thawing

Safety Precautions: Wear appropriate PPE (gloves, goggles) when handling. Avoid inhalation of powder.

4. Industry Applications and Case Studies

Pharmaceutical Quality Control

Used in batch testing of lipid-based drug formulations to ensure cholesterol content compliance with regulatory standards.

Clinical Diagnostics

Integrated into automated analyzers for high-throughput serum cholesterol screening in hospital laboratories.

5. Client Success Stories

Case Study 1: Biotech Research Institute

Challenge: Required precise quantification of membrane cholesterol in engineered liposomes.

Solution: Implemented TOOS-based assay with 0.5% CV across triplicate measurements.

Case Study 2: Diagnostic Laboratory Network

Challenge: Needed stable reagent for 10,000+ annual tests with FDA-compliant traceability.

Solution: Custom batch manufacturing with enhanced stability profile and full documentation.

6. Contact Us for Custom Solutions

Request technical documentation or discuss bulk ordering:

Email: info@vivalr.com
Phone: (86) 15866781826