sodium deoxycholate cas 302-95-4
Assay: 98%
Appearance: White powder, no odor and smell
Capacity: 500kg per year
Packaging: 25kg drum, foil bag
Sample: available
related documents:
COA of Sodium Deoxycholate CAS 302-95-4
TDS of Sodium Deoxycholate CAS 302-95-4
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Product Overview: Sodium Deoxycholate (CAS 302-95-4)
Table of Contents
Basic Information & Specifications
| Parameter | Sodium Deoxycholate | Similar Detergents (e.g., SDS) |
|---|---|---|
| CAS Number | 302-95-4 | 151-21-3 |
| Molecular Formula | C24H39NaO4 | C12H25NaO4S |
| Molecular Weight | 414.56 g/mol | 288.38 g/mol |
| Solubility | Water, ethanol | Water |
| Critical Micelle Concentration (CMC) | 2-4 mM | 8-10 mM |
| Primary Use | Mild detergent for membrane proteins | Strong denaturing agent |
Applications & Use Cases
Key Applications:
- Cell Lysis: Gentle disruption of cell membranes while preserving protein activity.
- Lipoprotein Solubilization: Effective in isolating lipoproteins for cardiovascular research.
- Virus Research: Stabilizes enveloped viruses during purification.
- Chromatography: Used in bile acid analysis via HPLC.
Industry-Specific Uses:
- Pharmaceuticals: Drug formulation excipient for solubility enhancement.
- Biotechnology: Protein extraction in antibody production.
- Diagnostics: Component of bacterial culture media.
Customer Case Studies
Case Study 1: Membrane Protein Extraction (ABC Biotech, 2024)
- Challenge: Low yield of functional GPCRs from mammalian cells.
- Solution: 0.5% sodium deoxycholate in lysis buffer.
- Result: 3x higher protein recovery vs. Triton X-100.
Case Study 2: Vaccine Development (XYZ Pharma, 2023)
- Challenge: Viral envelope degradation during purification.
- Solution: 0.1% sodium deoxycholate stabilization buffer.
- Result: 95% viral integrity maintained.
Usage Guidelines
Recommended Protocols:
| Application | Concentration | Buffer Compatibility |
|---|---|---|
| Cell Lysis | 0.1-0.5% | Tris-HCl, pH 7.4-8.0 |
| Protein Solubilization | 1-2% | PBS with 1mM EDTA |
Safety Notes:
- Store at 2-8°C in airtight container
- Use PPE when handling powder form
- Avoid strong oxidizers
Contact for Product Inquiries
Request technical specifications or pricing:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Ask about bulk orders (>100kg) and GMP-grade material.
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