Hydroxypropyl Methylcellulose Phthalate (HPMCP) CAS 9050-31-1: Comprehensive Product Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Use Cases
- 3. Technical Parameter Comparison
- 4. Industry Case Studies
- 5. Client Success Stories
- 6. Request Customized Solutions
1. Product Overview & Specifications
CAS Number: 9050-31-1
Molecular Formula: C₃₆H₅₄O₁₄
Appearance: White to off-white powder
Solubility: Soluble in acetone/water mixtures, insoluble in gastric fluids
Phthalyl Content: 18-24%
Viscosity (2% solution): 3-15 mPa·s
Key Features:
- pH-dependent solubility (dissolves above pH 5.0-5.5)
- Excellent film-forming properties
- USP-NF compliant for pharmaceutical applications
2. Key Applications & Use Cases
| Application Area | Technical Requirements | HPMCP Benefits |
|---|---|---|
| Enteric Coating | Gastric fluid resistance Controlled drug release |
Prevents API degradation Enhances bioavailability |
| Sustained Release Formulations | pH-sensitive dissolution Matrix formation |
Precise release profiles Improved patient compliance |
3. Technical Parameter Comparison
| Parameter | HPMCP | HPMCAS | Cellulose Acetate Phthalate |
|---|---|---|---|
| Dissolution pH | 5.0-5.5 | 5.5-6.0 | 6.0-6.5 |
| Film Flexibility | High | Medium | Low |
4. Industry Case Studies
Case 1: Enteric-coated Proton Pump Inhibitor Tablets
Challenge: Prevent rapid API degradation in gastric environment
Solution: 8% HPMCP coating layer applied via fluid bed system
Result: 98% drug release at intestinal pH within 45 minutes
Case 2: Moisture-sensitive Nutraceutical Encapsulation
Challenge: Maintain stability in high humidity conditions
Solution: HPMCP-based moisture barrier coating
Result: 89% reduction in moisture absorption
5. Client Success Stories
PharmaCo Solutions (Germany)
Application: Delayed-release antidepressant tablets
Outcome: Achieved 24-month shelf stability with <2% degradation
NutraHealth Inc. (USA)
Application: Enteric-coated probiotic formulations
Outcome: 10⁹ CFU viability maintained through gastric transit
6. Request Customized Solutions
Optimize your formulation with technical support from our experts:
Email: info@vivalr.com
Tel: (86) 15866781826



评论
目前还没有评论。