n-cyclohexyl-3-aminopropanesulfonic acid cas 1135-40-6

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COA of N-Cyclohexyl-3-aminopropanesulfonic acid(CAPS)
TDS of N-Cyclohexyl-3-aminopropanesulfonic acid(CAPS)

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n-Cyclohexyl-3-aminopropanesulfonic Acid (CAPS) CAS 1135-40-6: Ultimate Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter CAPS HEPES Tris
CAS Number 1135-40-6 7365-45-9 77-86-1
Effective pH Range 9.7-11.1 6.8-8.2 7.0-9.0
Temperature Sensitivity ±0.02 pH/°C ±0.014 pH/°C ±0.03 pH/°C
Metal Chelation No Yes No

2. Technical Applications & Usage Scenarios

Biochemical Applications

CAPS buffer demonstrates exceptional performance in:

  • Western blot transfer protocols (10-12% gel systems)
  • Enzyme kinetics studies above pH 9.5
  • High-resolution chromatography (HPLC/UPLC mobile phase adjustment)

Pharmaceutical Formulation

Preferred for:

  • Protein stabilization in lyophilized preparations
  • Ophthalmic solutions requiring alkaline pH maintenance
  • Transdermal delivery systems

3. Protocol Implementation & Case Studies

Case Study 1: Western Blot Optimization

Protocol: 25mM CAPS buffer with 20% methanol, pH 11.0
Result: 98% transfer efficiency for 150kDa proteins
Advantage: Reduced transfer time from 16hrs to 45min vs. traditional buffers

Case Study 2: Nanoparticle Synthesis

Application: Gold nanoparticle stabilization
Concentration: 50mM CAPS, pH 10.5
Outcome: 20nm particles with ±1.2nm size distribution

4. Industry-Specific Implementation Examples

Industry Application Typical Concentration
Diagnostics ELISA wash buffers 10-25mM
Biopharma Monoclonal antibody purification 50mM

5. Verified Client Success Stories

Client 1: European Biotech Leader

Challenge: Protein degradation in downstream processing
Solution: 40mM CAPS buffer in purification steps
Outcome: 30% yield improvement, 99.2% purity

Client 2: Asian Pharma Manufacturer

Issue: Unstable vaccine formulation
Implementation: CAPS-based lyoprotectant system
Result: 24-month stability at 2-8°C

6. Expert Consultation & Sample Request

Contact our technical specialists for:

  • Custom buffer formulation assistance
  • Application-specific protocol development
  • Bulk order specifications (GMP-grade available)

Email: info@vivalr.com
Phone: (86) 15866781826
Request product datasheet: [Your Name] [Company] [Application Details]

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