trans-4-phenyl-3-buten-2-one cas 1896-62-4

Chemical Name:trans-4-Phenyl-3-buten-2-one
CAS No.:1896-62-4
Molecular Formula: C10H10O
Molecular Weight:146.19
Appearance:Light yellow crystalline powder
Assay: 99%

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trans-4-Phenyl-3-buten-2-one (CAS 1896-62-4) Technical Guide

Table of Contents

1. Product Overview & Specifications

Parameter Value
Chemical Formula C10H10O
Molecular Weight 146.19 g/mol
Melting Point 38.5-41°C
Boiling Point 260-262°C
Flash Point 122°C
Density 1.038 g/cm³
Solubility Practically insoluble in water

2. Key Applications & Industrial Uses

Pharmaceutical Research: Functions as phospholipase A2 (PLA2) inhibitor with demonstrated immunosuppressive activity in Gram-negative pathogenic nematode studies.

Organic Synthesis: Critical intermediate for synthesizing complex molecules through conjugate addition reactions.

Material Science: Precursor for UV-absorbent polymers and specialty coatings.

3. Operational Guidelines

Storage: Maintain in airtight containers at 2-8°C with desiccant

Handling: Use nitrile gloves and chemical goggles in well-ventilated areas

Safety: R36/37/38 (Irritant) – Avoid inhalation and direct skin contact

4. Comparative Analysis with Derivatives

Compound CAS Molecular Formula Key Difference
Dibenzylideneacetone 538-58-9 C17H14O Extended conjugation system
4-Nitrobenzalacetone 3490-37-7 C10H9NO3 Electron-withdrawing nitro group

5. Industry Implementation Cases

Case 1: Leading European Pharma (Confidential) utilized batch No.TB-220913 in developing novel anti-inflammatory agents, achieving 73% PLA2 inhibition at 50μM concentration.

Case 2: Shanghai Tech University reported 92% yield in asymmetric catalysis trials using our GC≥98% grade material (2024 publication pending).

6. Technical Consultation

For analytical certificates, bulk pricing (25kg+), or custom synthesis requirements:

Email: info@vivalr.com
Tel: (86) 15866781826

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