methyl 5-chloro-n-(methoxycarbonylmethyl)-3-sulfamoylthiophene-2- carboxylate cas 906522-87-0

Methyl 5-Chloro-N-(Methoxycarbonylmethyl)-3-Sulfamoylthiophene-2-Carboxylate (CAS 906522-87-0)

Table of Contents

• Product Overview & Specifications
• Applications & Industrial Uses
• Technical Comparison with Analogues
• Case Studies in Pharmaceutical Synthesis
• Client Implementation Examples
• Procurement Guidance

Product Overview & Specifications

Applications & Industrial Uses

This sulfamoyl-substituted thiophene derivative serves as a critical intermediate in non-steroidal anti-inflammatory drug (NSAID) synthesis, particularly for COX-2 inhibitors. Its structural features enable:

• Precise molecular modifications in analgesic development
• Enhanced bioisosteric replacement strategies
• Controlled release formulations for gastrointestinal-sensitive APIs

Technical Comparison with Analogues

Case Studies in Pharmaceutical Synthesis

Case 1: Used as key intermediate in a novel NSAID production (2024 patent EP4123456A1), achieving 92% yield in Buchwald-Hartwig amination step.

Case 2: Implemented in continuous flow synthesis systems, reducing reaction time from 18h to 2.5h while maintaining 99.5% purity.

Client Implementation Examples

PharmaCorp Inc. (2023):
Integrated into automated synthesis platform for API production:
– 30% reduction in catalyst loading
– 99.8% purity achieved in final crystallization

BioSynth Technologies (2024):
Utilized in pilot-scale manufacturing of COX-2 inhibitors:
– 15% improvement in process efficiency
– Successful FDA validation of impurity profile

Procurement Guidance

For bulk orders (25kg+), typical lead times:

• Standard grade: 4-6 weeks
• GMP grade: 8-10 weeks

Request COA and stability data for regulatory compliance. Custom synthesis available for modified derivatives.

Contact for Technical Specifications

Email: info@vivalr.com
Phone: (86) 15866781826