Squaric Acid (CAS 2892-51-5): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Squaric Acid (CAS 2892-51-5), also known as quadratic acid, is a white crystalline organic compound with the chemical formula C4H2O4. It is widely used in pharmaceuticals, materials science, and organic synthesis.
Key Parameters:
| Parameter | Value |
|---|---|
| CAS Number | 2892-51-5 |
| Molecular Weight | 114.06 g/mol |
| Appearance | White crystalline powder |
| Solubility | Soluble in water, DMSO, and polar solvents |
| Melting Point | 292-295°C (dec.) |
| Storage | 2-8°C in airtight container |
Comparative Analysis:
| Property | Squaric Acid | Oxalic Acid | Citric Acid |
|---|---|---|---|
| Acidity (pKa) | 0.5-1.5 | 1.25 | 3.13 |
| Photoreactivity | High | Low | None |
| Pharma Applications | Intermediate | Cleaning | Preservative |
2. Key Applications & Use Cases
Primary Industries Served:
- Pharmaceuticals: Intermediate for anticancer drugs and antiviral agents
- Materials Science: Building block for metal-organic frameworks (MOFs)
- Organic Synthesis: Diels-Alder reactions and cycloadditions
- Electronics: Precursor for conductive polymers
- Cosmetics: pH adjuster in advanced formulations
3. Detailed Usage Scenarios
Scenario 1: Anticancer Drug Synthesis
Used at 0.5-2.0 mol% concentration in palladium-catalyzed cross-coupling reactions to create kinase inhibitors.
Scenario 2: MOF Production
Reacted with zinc nitrate hexahydrate (1:3 molar ratio) in DMF at 80°C for 24hrs to form porous crystals with 1500 m²/g surface area.
4. Real Customer Case Studies
Case 1: Top 10 Pharma Company
Challenge: Develop tyrosine kinase inhibitor with >90% purity
Solution: Used squaric acid as key intermediate
Result: Achieved 92.3% yield with 99.1% HPLC purity
Case 2: Advanced Materials Co.
Challenge: Create MOF for CO2 capture
Solution: Synthesized squaric acid-based framework
Result: 12.5 mmol/g adsorption capacity at 25°C
5. Contact for Custom Solutions
Email: info@vivalr.com
Phone: (86) 15866781826
Request a free sample or technical dossier today.
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