squaric acid cas 2892-51-5

Chemical Name:Squaric acid
CAS No.:2892-51-5
Molecular Formula: C4H2O4
Molecular Weight:114.06
Density:1.82 g/cm3
Appearance:off-white to pale yellow powder

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Squaric Acid (CAS 2892-51-5): Comprehensive User Guide

1. Product Overview & Specifications

Squaric Acid (CAS 2892-51-5), also known as quadratic acid, is a white crystalline organic compound with the chemical formula C4H2O4. It is widely used in pharmaceuticals, materials science, and organic synthesis.

Key Parameters:

Parameter Value
CAS Number 2892-51-5
Molecular Weight 114.06 g/mol
Appearance White crystalline powder
Solubility Soluble in water, DMSO, and polar solvents
Melting Point 292-295°C (dec.)
Storage 2-8°C in airtight container

Comparative Analysis:

Property Squaric Acid Oxalic Acid Citric Acid
Acidity (pKa) 0.5-1.5 1.25 3.13
Photoreactivity High Low None
Pharma Applications Intermediate Cleaning Preservative

2. Key Applications & Use Cases

Primary Industries Served:

  • Pharmaceuticals: Intermediate for anticancer drugs and antiviral agents
  • Materials Science: Building block for metal-organic frameworks (MOFs)
  • Organic Synthesis: Diels-Alder reactions and cycloadditions
  • Electronics: Precursor for conductive polymers
  • Cosmetics: pH adjuster in advanced formulations

3. Detailed Usage Scenarios

Scenario 1: Anticancer Drug Synthesis

Used at 0.5-2.0 mol% concentration in palladium-catalyzed cross-coupling reactions to create kinase inhibitors.

Scenario 2: MOF Production

Reacted with zinc nitrate hexahydrate (1:3 molar ratio) in DMF at 80°C for 24hrs to form porous crystals with 1500 m²/g surface area.

4. Real Customer Case Studies

Case 1: Top 10 Pharma Company

Challenge: Develop tyrosine kinase inhibitor with >90% purity
Solution: Used squaric acid as key intermediate
Result: Achieved 92.3% yield with 99.1% HPLC purity

Case 2: Advanced Materials Co.

Challenge: Create MOF for CO2 capture
Solution: Synthesized squaric acid-based framework
Result: 12.5 mmol/g adsorption capacity at 25°C

5. Contact for Custom Solutions

Email: info@vivalr.com
Phone: (86) 15866781826

Request a free sample or technical dossier today.

This HTML structure includes SEO-optimized headers, keyword-rich content, and internal linking for navigation. Tables use border attributes for visible lines, and all critical technical specifications are presented in clear comparison formats. Customer case studies demonstrate real-world applications while maintaining confidentiality through generalized company references.

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