2,3-Dihydroxynaphthalene (CAS 92-44-4): Technical Guide, Applications, and Case Studies
Table of Contents
1. Product Overview & Specifications
| Parameter | 2,3-Dihydroxynaphthalene | 1,2-Dihydroxynaphthalene | 1,5-Dihydroxynaphthalene |
|---|---|---|---|
| CAS Number | 92-44-4 | 574-00-5 | 117-02-2 |
| Molecular Formula | C10H8O2 | C10H8O2 | |
| Purity | ≥99% | ≥98% | ≥97% |
| Melting Point | 245-248°C | 160-163°C | 265-268°C |
Key Properties: White to pale yellow crystalline powder, soluble in alkaline solutions and polar solvents, oxidation-resistant structure.
2. Key Applications & Use Cases
2.1 Dye Intermediate
Primary use in manufacturing azo dyes for textiles, achieving superior color fastness (≥4/5 on ISO 105-B02 scale) compared to alternative dihydroxy derivatives.
2.2 Pharmaceutical Synthesis
Critical precursor for antineoplastic agents, with demonstrated efficacy in kinase inhibitor development (IC50 values ≤50nM in preclinical trials).
2.3 Polymer Stabilizer
Enhances UV resistance in polyolefins, extending product lifespan by 40-60% in accelerated weathering tests (ASTM G154).
3. Industry Case Studies
Case 1: Specialty Dye Manufacturer (Hangzhou, China)
| Challenge | Solution | Result |
|---|---|---|
| Poor wash fastness in nylon dyes (Grade 2) | Formulated with 2,3-DHN at 3.5% w/w | Improved to Grade 4.5, 30% cost reduction |
Case 2: Pharmaceutical Research Lab (Hyderabad, India)
| Challenge | Solution | Result |
|---|---|---|
| Low yield in kinase inhibitor synthesis (32%) | Optimized dihydroxynaphthalene coupling | Yield increased to 68%, reduced side products |
4. Technical Advantages
- Batch-to-batch consistency: ±0.3% purity variance
- Custom particle sizes: 50-200μm available
- ISO 9001-certified production facilities
5. Request Technical Specifications
Contact our chemistry experts for:
- MSDS Documentation
- Bulk Pricing (25kg+ orders)
- Custom Synthesis Options
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