p-Hydroxybenzoic acid CAS 99-96-7

Chemical Name: P-hydroxybenzoic acid
CAS No.: 99-96-7
Molecular Fomula: H8N2O8S2
Molecular weight: 228.2
Appearance: White crystalline powder
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p-Hydroxybenzoic Acid (CAS 99-96-7): Comprehensive User Guide

1. Product Overview & Specifications

Chemical Profile

  • CAS Number: 99-96-7
  • IUPAC Name: 4-Hydroxybenzoic acid
  • Molecular Formula: C7H6O3
  • Molar Mass: 138.12 g/mol

Technical Specifications Comparison

Parameter Pharmaceutical Grade Industrial Grade Food Grade
Purity (%) ≥99.5 ≥98.0 ≥99.0
Melting Point 214-217°C 213-215°C 214-216°C
Heavy Metals ≤10 ppm ≤50 ppm ≤20 ppm

2. Key Applications & Industry Uses

Pharmaceutical Manufacturing

Essential intermediate for:

  • Paraben-based preservatives
  • Antiseptic formulations
  • Co-crystal engineering

Food Preservation Systems

  • pH-stable antimicrobial agent (E-number: E214-E219)
  • Effective against yeast/mold in baked goods
  • Dairy product shelf-life extension

Cosmetic Chemistry

  • Preservative booster in emulsion systems
  • Synergistic with phenoxyethanol
  • pH range: 4-8 optimal performance

3. Usage Guidelines & Best Practices

Solubility Management

Solvent Solubility (g/100ml) Temperature
Water 0.5 25°C
Ethanol 45.7 25°C

Formulation Tips

  • Optimal concentration: 0.1-0.3% w/w
  • Combine with chelating agents for enhanced efficacy
  • Avoid strong oxidizers in storage

4. Real-World Case Studies

Case 1: Dairy Preservation System

Client: European Dairy Consortium

  • Challenge: Extend yogurt shelf-life by 30%
  • Solution: 0.2% p-Hydroxybenzoic acid + calcium propionate
  • Result: 42-day microbial stability achieved

Case 2: Topical Antiseptic Formulation

Client: PharmaTech Inc. (USA)

  • Challenge: Develop alcohol-free surgical scrub
  • Solution: 1.5% p-Hydroxybenzoic acid + chlorhexidine
  • Result: 99.99% pathogen reduction (EN 1276)

5. Technical Inquiry & Ordering

Request customized specifications or bulk pricing:

Our chemical engineers will respond within 2 business hours with:

  • Material Safety Data Sheet (MSDS)
  • Regulatory compliance documentation
  • Logistics solutions

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