Cholesteryl Chloroformate (CAS 7144-08-3): Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Cholesteryl Chloroformate |
|---|---|
| CAS Number | 7144-08-3 |
| Molecular Formula | C28H45ClO2 |
| Molecular Weight | 449.11 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Storage Conditions | 2-8°C in airtight container |
2. Key Applications & Use Cases
2.1 Pharmaceutical Intermediate
Widely used in synthesis of cholesterol-based drug delivery systems, particularly for:
- Liposome functionalization
- Targeted cancer therapeutics
- Ocular drug formulations
2.2 Material Science
- Surface modification of biomedical polymers
- Preparation of cholesterol-containing liquid crystals
- Functional coatings for medical devices
3. Performance Comparison
| Property | Cholesteryl Chloroformate | Cholesteryl Acetate | Cholesteryl Oleyl Carbonate |
|---|---|---|---|
| Reactivity | High (active chloroformate group) | Low | Moderate |
| Bioconjugation Efficiency | 92-98% | N/A | 40-60% |
4. Industry Implementation Examples
4.1 Liposomal Drug Delivery Systems
Used in development of Doxorubicin-loaded stealth liposomes showing:
- 30% increased circulation time
- 15% higher tumor accumulation vs standard formulations
5. Client Success Stories
Case 1: PharmaBio Solutions
Challenge: Needed stable conjugation of antibodies to lipid nanoparticles
Solution: Used 7144-08-3 as coupling agent
Result: Achieved 95% binding efficiency with 6-month stability
Case 2: PolymerTech Industries
Developed antimicrobial catheter coatings using our cholesteryl chloroformate, reducing infection rates by 68% in clinical trials.
6. Request Customized Solutions
Contact our technical team for:
- Bulk pricing (1kg+ orders)
- Custom synthesis options
- Application-specific purity grades
Email: info@vivalr.com
Phone: (86) 15866781826
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