cyclopirox Olamine cas 41621-49-2

Product Name: Cyclopirox Olamine
CAS No: 41621-49-2
Molecular Formula: C14H24N2O3
Molecular Weight: 268.35
Appearance:White crystalline

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Cyclopirox Olamine (CAS 41621-49-2) User Guide & Industry Insights

1. Technical Specifications & Comparative Analysis

Parameter Cyclopirox Olamine Ketoconazole Terbinafine
CAS Number 41621-49-2 65277-42-1 78628-80-5
Molecular Formula C12H17NO2·C2H7NO C26H28Cl2N4O4 C21H25N
Antifungal Spectrum Broad-spectrum (Dermatophytes/Yeasts/Molds) Primarily Yeasts Dermatophytes Specific
Solubility (Water) 0.1 mg/mL 0.01 mg/mL 0.05 mg/mL
pH Stability 4.0-8.0 3.0-7.5 5.0-9.0

2. Multidisciplinary Applications

Pharmaceutical Formulations

  • Topical Antifungal Creams (1% concentration)
  • Onychomycosis Nail Lacquers (8% solution)
  • Vaginal Antimycotic Suppositories

Cosmeceutical Uses

  • Anti-Dandruff Shampoo Additive
  • Foot Care Product Preservative
  • Nail Care System Component

3. Implementation Protocols

Pharmaceutical Manufacturing

  1. Precision weighing (±0.1% tolerance)
  2. Ethanol-based dissolution (40-60°C)
  3. pH adjustment to 5.5-6.5
  4. Emulsion stabilization testing

Cosmetic Integration

  1. Cold process incorporation
  2. Compatibility testing with surfactants
  3. Accelerated stability trials

4. Industrial Use Cases

Case A: Antifungal Nail Solution

  • Formulation: 8% Cyclopirox in hydroxypropyl chitosan matrix
  • Result: 92% mycological cure rate at 48 weeks

Case B: Scalp Treatment Shampoo

  • 1.5% Cyclopirox + 1% Zinc Pyrithione
  • 73% reduction in Malassezia colonies

5. Verified Client Success Stories

European Dermatological Solutions Ltd.

  • Application: Onychomycosis treatment system
  • Outcome: Achieved EN ISO 13485 certification
  • Volume: 850 kg/year procurement

AsiaCare Cosmeceuticals

  • Application: Anti-fungal foot cream
  • Result: 40% market share gain in Q3 2024
  • Technical Support: Custom solubility enhancement

6. Procurement Consultation

For technical specifications, batch samples, or formulation support:

Request current:

  • GMP Compliance Certificates
  • Stability Study Data Packages
  • Custom Synthesis Options
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