Trifluoromethanesulfonyl Chloride (CAS 421-83-0) Ultimate Procurement & Application Guide 2024
Contents
- Product Specifications & Comparative Analysis
- Industrial Applications & Functional Mechanisms
- Operational Guidelines & Safety Protocols
- Case Studies: Real-World Implementations
- Strategic Supplier Selection Criteria
Technical Specifications & Competitive Benchmarking
| Parameter | Trifluoromethanesulfonyl Chloride | Triflic Acid | Methanesulfonyl Chloride |
|---|---|---|---|
| CAS Number | 421-83-0 | 1493-13-6 | 124-63-0 |
| Molecular Formula | CF3SO2Cl | CF3SO3H | CH3SO2Cl |
| Molecular Weight | 184.52 g/mol | 150.08 g/mol | 114.55 g/mol |
| Appearance | Colorless liquid | Colorless liquid | Clear liquid |
| Boiling Point | 155-158°C | 162°C | 161°C |
| Density | 1.64 g/cm³ | 1.696 g/cm³ | 1.48 g/cm³ |
Core Applications Across Industries
Pharmaceutical Intermediate Synthesis
Enables production of trifluoromethanesulfonates for antiviral APIs and kinase inhibitors
Agrochemical Manufacturing
Key component in fluorinated pesticides and herbicides formulations
Polymer Chemistry
Used as superacid precursor for cationic polymerization catalysts
Electronics Industry
Essential in lithium battery electrolyte formulations
Research & Development
Versatile reagent for organofluorine compound synthesis
Operational Best Practices
Safety Requirements
Mandatory PPE: Chemical-resistant gloves, face shield, vapor respirator
Storage Conditions
Store under dry inert gas at 2-8°C in amber glass containers
Handling Protocols
Use closed systems with nitrogen blanketing during transfer operations
Documented Implementation Cases
Case 1: Pharmaceutical Process Optimization
Client: Top-10 Global API Manufacturer
Challenge: Improve yield in remdesivir intermediate production
Solution: Optimized triflation reaction conditions using our chloride
Result: 22% yield increase, 99.5% HPLC purity achieved
Case 2: Advanced Herbicide Development
Client: EU Agrochem Leader
Challenge: Develop moisture-resistant fluorinated herbicide
Solution: Customized purification process for enhanced stability
Result: Field efficacy duration extended by 40%
Case 3: Battery Electrolyte Innovation
Client: Lithium Battery Producer
Challenge: Enhance high-temperature performance
Solution: Formulation with ultra-pure trifluoromethanesulfonyl chloride
Result: 15% capacity improvement at 60°C
Supplier Evaluation Framework
| Criterion | Industry Standard | Our Offering |
|---|---|---|
| Purity Level | ≥99% | 99.9% (GC verified) |
| Moisture Content | ≤500ppm | ≤50ppm (Karl Fischer) |
| Package Size | 25kg drum | 1kg-500kg customizable |
| Lead Time | 4-6 weeks | 2 weeks (stocked material) |
Contact for Technical Consultation
Email: info@vivalr.com
Phone: (86) 15866781826
Office Hours: Mon-Fri 08:00-17:00 GMT+8
Why Choose Us?
- ISO 9001 & REACH certified production
- Batch-to-batch consistency guaranteed
- Custom synthesis services available
- Global logistics network with temperature control
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